Table 2 Outcome of follow-up for all patients with cyst

Follow-up period, median (range), months

59 (13 - 177)

Age at final examination, median (range), years

76 (32 - 99)

Further therapy due to worsening of cyst

12

  Appearance of mural nodule

6

  MPD ≥10 mm

1

  Appearance of mural nodule + MPD ≥10 mm

2

  Cyst Diameter ≥30 mm plus patient’s proposal

2

  Penetration to stomach plus cyst Diameter ≥30 mm

1

  Surgical specimen

9

  Pancreatic juice cytology plus imaging examinations

3

  IPMN with LGD

5

  IPMN with HGD

3

  Equivalent to IPMN with HGD^a

   MPD ≥10 mm, cytologically positive for HGD, not resected case

   Mural nodule positive, cytologically positive for LGD, not resected case

2

   IPMN associated with invasive carcinoma (stage 3, UICC 8^th ed.)^a

(not resected case)

1

   SCN

1

   Duration time from initial diagnosis to onset of IPMN with HGD or associated invasive carcinoma, median (range), months

85 (24 - 174)

Concomitant PDAC

14

 Stage 0, 1, 2a, 2b, 3, 4

0,0,8,4,0,2

  Surgical specimen

12

  EUS-FNA plus imaging examinations

2

  Duration time from initial diagnosis to onset of concomitant PDAC, median (range), months

45 (14 - 119)