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Table 1 Comparison of 2010 and 2019 WHO Criteria for Serrated Polyposis Syndrome (SPS)

From: Body Mass Index, sex, non-steroidal anti-inflammatory drug medications, smoking and alcohol are differentially associated with World Health Organisation criteria and colorectal cancer risk in people with Serrated Polyposis Syndrome: an Australian case-control study

Major SPS Phenotypes

WHO Criteria 2010

WHO Criteria 2019

Type 1

I. At least 5 serrated polyps proximal to the sigmoid Colon, 2 of which are > 10 mm in diameter.α

I. ≥5 Serrated lesions/polyps proximal to the rectum, all being ≥5 mm in size, with at least 2 being ≥10 mm in size

 

II. Any number of serrated polyps occurring proximal to the sigmoid Colon in an individual who has a first-degree relative with SPS.

 

Type 2

III. > 20 serrated polyps of any size distributed throughout the Colon.α

II. > 20 Serrated lesions/polyps of any size distributed throughout the large bowel, with ≥5 being proximal to the rectum.

  1. α criteria used to define SPS in this study