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Table 1. Diagnostic performance of H. pylori stool antigen test in southwestern Uganda

From: Diagnostic performance of fecal Helicobacter pylori antigen test in Uganda

 

16s rRNA

Fecal antigen

n (%)

sensitivity

specificity

PPV

NPV

LR-

LR+

NND

Men, n=72

Positive

Positive

26 (36.11)

0.81 (0.62, 1.00)

0.97 (0.91, 1.04)

0.96 (0.86, 1.06)

0.87 (0.73, 1.01)

0.19 (-0.01, 0.39)

32 (-57, 122)

1.21 (0.95, 1.46)

  

Negative

6 (8.33)

 

Negative

Positive

1 (1.39)

  

Negative

39 (54.17)

Women, n=78

Positive

Positive

31 (39.74)

0.89 (0.74,1.03)

0.98 (0.91, 1.04)

0.97 (0.88,1.05)

0.91 (0.80,1.03)

0.12 (-0.04, 0.27)

38 (-67,143)

1.13 (0.95, 1.32)

  

Negative

4 (5.13)

 

Negative

Positive

1 (1.28)

  

Negative

42 (53.85)

All, n=150

Positive

Positive

57 (38)

0.85 (0.76, 0.94)

0.96 (0.94, 1.01)

0.97 (0.92, 1.01)

0.89 (0.83, 0.95)

0.15 (0.06, 0.24)

35 (-13, 84)

1.17 (1.06, 1.28)

  

Negative

10 (6.7)

 

Negative

Positive

2 (1.3)

  

Negative

81 (54)

  1. PPV Positive Predictive Value, NPV Negative Predictive Value, LR- Likelihood Ratio of a negative test, LR+ Likelihood Ratio of a positive test, NND Number Needed to Diagnose. H. pylori stool antigen test accuracy for overall sample is 0.92 (95%CI 0.88, 0.96); for women only is 0.94 (95%CI 0.86, 1.01); and men only is 0.90 (95%CI 0.81, 0.99). F1 score for overall sample is 0.90 (95%CI 0.85, 0.96); for women only is 0.92 (95%CI 0.83, 1.02); and men only is 0.88 (95% CI 0.76, 1.00)