Table 4 Univariate and multivariate analysis of factors associated with early gastroesophageal varices

OR(95%CI)

P

OR(95%CI)

Age (years)

1.004 (0.989, 1.020)

0.612

Male, n(%)

0.865 (0.600, 1.247)

0.436

Aetiology of cirrhosis (HBV/HCV/other)

0.839 (0.643, 1.095)

0.197

Child category (A/B)

2.158 (0.988, 4.713)

0.054

ALT(U/L)

1.001 (1.000, 1.001)

0.246

AST(U/L)

1.001 (1.000, 1.002)

0.046

TBIL (umol/L)

1.008 (1.000, 1.016)

0.041

1.003 (0.995, 1.011)

ALB(g/L)

0.981 (0.949, 1.015)

0.247

PLT(×10⁹/L)

0.996 (0.993, 1.000)

0.034

PT(s)

1.056 (0.971, 1.149)

0.205

Hyaluronic acid (ng/ml)

1.001 (1.001, 1.002)

<0.001

1.000 (0.999, 1.001)

Laminin (ng/ml)

1.015 (1.009, 1.020)

<0.001

1.011 (1.004, 1.018)

type III pro-collagen (ng/ml)

1.040 (1.012, 1.069)

0.005

1.001 (0.966, 1.037)

Collagen type IV (ng/ml)

1.004 (1.001, 1.006)

0.002

0.999 (0.995, 1.002)

LS (Kpa)

1.032 (1.113, 1.051)

0.001

1.012 (0.987, 1.037)

Splenic diameter (mm)

1.003 (0.993, 1.013)

0.569

APRI

1.080 (1.012, 1.151)

0.019

0.976 (0.886, 1.075)

FIB-4

1.121 (1.042, 1.206)

0.002

1.036 (0.924, 1.161)