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Table 2 The pathological histological scoring

From: Triclosan exposure induced disturbance of gut microbiota and exaggerated experimental colitis in mice

Inflammation

Depth of the lesion

Extent of disease (%)

Crypt destruction

Score

none

none

none

none

0

Mild, inflammatory cells infiltration mucous layer < 1/3

Mucous membrane layer

1–25

1/3 of the basement crypt was destroyed

1

Moderate, inflammatory cell infiltration was more than 1/3 of the full mucosal layer but less than 2/3 of the mucosal layer

Mucosa and submucosa

26–50

2/3 of the basement crypts were destroyed

2

Serious, the infiltration of inflammatory cells exceeded 2/3 of the total mucosal layer

Full-thickness inflammation

51–75

Only part of the epithelium is intact

3

  

76–100

All crypts and epithelium are damaged

4