Inflammation | Depth of the lesion | Extent of disease (%) | Crypt destruction | Score |
---|---|---|---|---|
none | none | none | none | 0 |
Mild, inflammatory cells infiltration mucous layer < 1/3 | Mucous membrane layer | 1–25 | 1/3 of the basement crypt was destroyed | 1 |
Moderate, inflammatory cell infiltration was more than 1/3 of the full mucosal layer but less than 2/3 of the mucosal layer | Mucosa and submucosa | 26–50 | 2/3 of the basement crypts were destroyed | 2 |
Serious, the infiltration of inflammatory cells exceeded 2/3 of the total mucosal layer | Full-thickness inflammation | 51–75 | Only part of the epithelium is intact | 3 |
76–100 | All crypts and epithelium are damaged | 4 |