Table 1 Baseline characteristics of gastric cancer patients per hypertension and medications
Characteristics | no HT | Treated HT | Untreated HT | P |
|---|---|---|---|---|
Number | 2203 | 312 | 497 | |
Age (year) | 56.92 (11.31) | 64.51 (9.2) | 61.50 (10.46) | < 0.001 |
Male (N%) | 1636 (74.26%) | 230 (73.71%) | 373 (75.05%) | 0.904 |
Smoking (N %) | 409 (20.70%) | 63 (20.25%) | 84 (16.90%) | 0.158 |
Alcohol (N %) | 118 (5.98%) | 20 (6.43%) | 30 (6.03%) | 0.955 |
Family history (N %) | 178 (9.03%) | 36 (11.61%) | 44 (8.85%) | 0.324 |
BMI (kg/m2) | 22.44 (2.98) | 24.33 (3.13) | 23.35 (3.03) | < 0.001 |
CCB (N%) | NA | 149 (50.96%) | NA | |
ACEI/ARB (N%) | NA | 52 (16.67%) | NA | |
Diuretic (N%) | NA | 7 (2.24%) | NA | |
b-blocker (N%) | NA | 15 (4.81%) | NA | |
Unclear (N%) | NA | 116 (37.18%) | NA | |
SBP (mmHg) | 115.11 (12.06) | 144.3 (13.63) | 152.35 (14.46) | < 0.001 |
DBP (mmHg) | 72.55 (8.63) | 88.16 (9.04) | 88.58 (10.43) | < 0.001 |
FPG (mmol/L) | 5.93 (2.27) | 6.9 (2.63) | 6.83 (2.86) | < 0.001 |
TG (mmol/L) | 1.17 (0.87) | 1.32 (0.85) | 1.31 (0.95) | < 0.001 |
TC (mmol/L) | 4.46 (1.04) | 4.69 (1.1) | 4.67 (1.14) | < 0.001 |
HDL (mmol/L) | 1.05 (0.40) | 1.02 (0.37) | 1.01 (0.37) | 0.011 |
LDL (mmol/L) | 2.92 (0.90) | 3.16 (0.9) | 3.11 (0.97) | < 0.001 |
TNM stage (N%) | 0.052 | |||
I | 248 (12.18%) | 39 (12.50%) | 57 (11.52%) | |
II | 308 (15.13%) | 53 (16.99%) | 63 (12.73%) | |
III | 1167 (57.32%) | 178 (57.05%) | 271 (51.75%) | |
IV | 313 (15.37%) | 42 (13.46%) | 104 (21.01%) | |
Pathological type (N%) | 0.696 | |||
adenocarcinoma | 1519 (76.87%) | 243 (78.90%) | 385 (78.09%) | |
signet-ring cell | 424 (21.46%) | 58 (18.83%) | 100 (20.28%) | |
neuroendocrine | 16 (0.81%) | 3 (0.97%) | 6 (1.22%) | |
Other | 17 (0.86%) | 4 (1.30%) | 2 (0.41%) | |
Differentiated | 0.682 | |||
High | 22 (1.11%) | 6 (1.95%) | 6 (1.22%) | |
Middle | 745 (37.72%) | 121 (39.29%) | 180 (36.51%) | |
Low | 1208 (61.16%) | 181 (58.77%) | 307 (62.27%) | |
Chemotherapy (N %) | 700 (31.77%) | 101 (32.4%) | 151 (30.4%) | 0.792 |
Chemotherapy courses (N) | 3.67 (2.4) | 3.32 (2.3) | 3.40 (2.3) | 0.161 |