Outcomes | No. | Events | Follow-up duration (years)a | Event Rate (/100,000 Person-Years) | Crude HR (95% CI) | P-value |
---|---|---|---|---|---|---|
CRC | Â | Â | Â | Â | Â | Â |
  1–2 components | 78,274 | 792 | 4.39 (2.61–6.29) | 223.09 | Reference | < 0.001 |
  3–4 components | 41,569 | 526 | 4.35 (2.62–6.23) | 280.85 | 1.26 (1.13–1.41) | |
All-cause mortality | Â | Â | Â | Â | Â | Â |
  1–2 components | 78,274 | 6,781 | 4.42 (2.64–6.32) | 1900.11 | Reference |  |
  3–4 components | 41,569 | 3,947 | 4.39 (2.65–6.26) | 2094.32 | 1.10 (1.06–1.15) | < 0.001 |
All comparisons were based on matched cohorts. Significant values are showing in bold. a Presented in medium (Q1-Q3). | ||||||
Abbreviations: CRC, colorectal cancer; HR, hazard ratio. |