Association between serum uric acid-to-creatinine ratio and non-alcoholic fatty liver disease: a cross-sectional study in Chinese non-obese people with a normal range of low-density lipoprotein cholesterol

Table 4 Relationship between UA/Scr ratio and NAFLD in different sensitivity analyses

Exposure	Model I (OR,95%CI, P)	Model II (OR,95%CI, P)	Model III (OR,95%CI, P)	Model IV (OR,95%CI, P)
SUA/Scr	1.445 (1.414, 1.477) < 0.00001	1.413 (1.382, 1.444) < 0.00001	1.428 (1.399, 1.458) < 0.00001	1.278 (1.121, 1.456) 0.00023
SUA/Scr (Quintile)
Q1	Ref	Ref	Ref	Ref
Q2	1.308 (1.217, 1.404) < 0.00001	1.268 (1.184, 1.358) < 0.00001	1.281 (1.198, 1.370) < 0.00001	1.161 (0.908, 1.484) 0.23352
Q3	1.662 (1.552, 1.779) < 0.00001	1.587 (1.485, 1.695) < 0.00001	1.596 (1.497, 1.703) < 0.00001	1.512 (1.159, 1.973) 0.00230
Q4	2.028 (1.895, 2.170) < 0.00001	1.914 (1.793, 2.043) < 0.00001	1.944 (1.824, 2.072) < 0.00001	1.735 (1.277, 2.358) 0.00043
Q5	2.735 (2.552, 2.932) < 0.00001	2.546 (2.380, 2.724) < 0.00001	2.611 (2.446, 2.787) < 0.00001	1.843 (1.211, 2.804) 0.00430
P for trend	< 0.00001	< 0.00001	< 0.00001	0.00001

Model I was sensitivity analysis in participants without FPG > 6.1 mmol/L (n = 171,532). We adjusted age, sex, BMI, eGFR, ALT, AST, GGT, ALB, GLB, DBIL, TB, BUN, FBG, TG, HDL-c, LDL-c
Model II was sensitivity analysis in participants without ALT > 40U/L (n = 169,898). We adjusted age, sex, BMI, eGFR, ALT, AST, GGT, ALB, GLB, DBIL, TB, BUN, FBG, TG, HDL-c, LDL-c
Model III was sensitivity analysis in participants with eGFR ≥ 60 ml/min/1.73m² (n = 178,481). We adjusted age, sex, BMI, eGFR, ALT, AST, GGT, ALB, GLB, DBIL, TB, BUN, FBG, TG, HDL-c, LDL-c
Model IV was sensitivity analysis in participants with eGFR < 60 ml/min/1.73m² (n = 3839). We adjusted age, sex, BMI, eGFR, ALT, AST, GGT, ALB, GLB, DBIL, TB, BUN, FBG, TG, HDL-c, LDL-c
OR odds ratios; CI confidence, Ref reference; SUA/Scr serum uric acid-to-creatinine ratio

ISSN: 1471-230X