Table 2 ROC curve analysis and univariate logistic regression analysis of predictors for HCC onset
Variables | ROC curves | Logistic regression | |||||
|---|---|---|---|---|---|---|---|
AUC | Cutoff | Sensitivity | Specificity | OR | 95% CI | p value | |
Gender | 0.510 | Female | 0.169 | 0.851 | 0.88 | 0.58–1.35 | 0.565 |
Age | 0.509 | 58.50 | 0.545 | 0.519 | 1.01 | 0.99–1.02 | 0.469 |
ALT | 0.683 | 95.35 | 0.929 | 0.422 | 0.99 | 0.99–1.00 | 0.001 |
AST | 0.647 | 51.50 | 0.714 | 0.552 | 1.00 | 0.99–1.00 | 0.005 |
GGT | 0.609 | 72.35 | 0.578 | 0.656 | 1.00 | 1.00–1.00 | 0.006 |
Albumin | 0.588 | 43.55 | 0.331 | 0.831 | 1.03 | 1.00–1.06 | 0.045 |
Total bilirubin | 0.555 | 27.50 | 0.786 | 0.377 | 1.00 | 0.99–1.00 | 0.123 |
Alb/Glo | 0.585 | 1.25 | 0.734 | 0.403 | 1.44 | 0.97–2.14 | 0.072 |
Lymphocyte | 0.563 | 1.005 | 0.403 | 0.740 | 0.78 | 0.60–1.00 | 0.048 |
PDW | 0.571 | 16.15 | 0.819 | 0.364 | 0.93 | 0.88–0.99 | 0.021 |
MPV | 0.561 | 11.85 | 0.696 | 0.455 | 0.87 | 0.76–1.00 | 0.054 |
AFP | 0.659 | 29.70 | 0.474 | 0.851 | 1.00 | 1.00–1.00 | 0.058 |
AFP-L3 | 0.687 | 13.50 | 0.461 | 0.955 | 1.02 | 1.01–1.02 | 0.000 |
TB/ALB | 0.578 | 0.754 | 0.786 | 0.370 | 0.83 | 0.68–1.01 | 0.069 |
GPR | 0.588 | 0.450 | 0.461 | 0.727 | 0.92 | 0.84–1.02 | 0.122 |
HBsAg | 0.649 | Positive | 0.818 | 0.481 | 3.00 | 1.99–4.53 | 0.000 |
HBeAg | 0.575 | Negative | 0.955 | 0.195 | 0.32 | 0.15–0.68 | 0.003 |