Table 2 Baseline characteristics of EAD versus non-EAD patients
Whole cohort (n = 231) | Study cohort (n = 110) | Non-EAD (n = 62) | EAD (n = 48) | p-value | |
|---|---|---|---|---|---|
Donor and Graft | |||||
Age (years) | 58 (47–71) | 60 (48–73) | 60 (48–71) | 61 (50–74) | 0.523 |
Female gender | 98 (42.4%) | 47 (42.7%) | 29 (46.8%) | 18 (37.5%) | 0.329 |
BMI (n = 109) | 25.5 (23.0–28.0) | 26 (23–28) | 25 (22.5–28) | 26 (24–29) | 0.473 |
Split liver transplantation | 7 (3.0%) | 3 (2.7%) | 3 (4.8%) | 0 | 0.255 |
DCD | 68 (29.4%) | 30 (27.3%) | 8 (12.9%) | 22 (45.8%) | < 0.001 |
Cold ischemia time (h) (n = 106) | 7.0 (5.8–8.4) | 7.1 (5.8–8.7) | 6.5 (5.4–8.4) | 7.4 (6.6–9.6) | 0.013 |
Warm ischemia time (min) | 34.0 (30.0–38.0) | 34.5 (29.8–38.3) | 34.5 (31.5–44.0) | 33.5 (29.0–38.3) | 0.504 |
Recipient | |||||
Age (years) | 57 (48–63) | 57 (48–64) | 57 (46–63) | 58 (50–64) | 0.708 |
Female gender | 76 (32.9%) | 36 (32.7%) | 19 (30.6%) | 17 (35.4%) | 0.597 |
Body mass index | 27.0 (22.7–30.1) | 27.4 (23.5–30.9) | 27.3 (23.2–30.6) | 27.9 (23.9–31.7) | 0.849 |
Charlson-Comorbidity-Index | 5 (3–6) | 5 (3–5) | 5 (3–5) | 5 (3–5) | 0.606 |
Serum-Creatinine (µmol/l) (n = 81) | 88 (68–133) | 93 (68–145) | 91 (71–156) | 94 (66–122) | 0.384 |
Preoperative RRT | 53 (22.9%) | 28 (25.5%) | 17 (27.4%) | 11 (22.9%) | 0.591 |
Laboratory MELD-score (n = 109) | 19 (11–31) | 20 (12–33) | 23 (16–34) | 17 (9–31) | 0.029 |
Liver cirrhosis (Child–Pugh-Score) | 0.147 | ||||
No cirrhosis | 40 (17.3%) | 21 (19.1%) | 11 (17.7%) | 10 (20.8%) | |
A | 54 (23.4%) | 20 (18.2%) | 9 (14.5%) | 11 (22.9%) | |
B | 63 (27.3%) | 27 (24.5%) | 13 (21.0%) | 14 (39.2%) | |
C | 73 (31.6%) | 41 (37.3%) | 29 (46.8%) | 12 (25.0%) | |
Liver disease | 0.125 | ||||
Alcohol related liver disease | 66 (28.6%) | 35 (31.8%) | 21 (33.9%) | 14 (29.2%) | |
Non-alcoholic steatohepatitis | 20 (8.7%) | 12 (10.9%) | 8 (12.9%) | 4 (8.3%) | |
Viral hepatitis | 56 (24.2%) | 22 (20.0%) | 9 (14.5%) | 13 (27.1%) | |
Biliary liver disease | 22 (9.5%) | 9 (8.2%) | 8 (12.9%) | 1 (2.1%) | |
Other | 58 (25.1%) | 32 (29.1%) | 16 (25.8%) | 16 (33.3%) | |
Acute liver failure | 20 (8.7%) | 13 (11.8%) | 6 (9.7%) | 7 (14.6%) | 0.429 |
Carcinoma | 0.346 | ||||
HCC | 96 (41.6%) | 44 (40.0%) | 25 (40.3%) | 19 (39.6%) | |
CCC | 2 (0.9%) | 2 (1.8%) | 0 | 2 (4.2%) | |
Transplant procedure | |||||
Operation time (min) | 270 (218–325) | 235 (207–301) | 236 (210–291) | 233 (198–314) | 0.995 |
Transfusion requirements | |||||
EC | 1 (0–3) | 1 (0–3) | 1 (0–3) | 1 (0–3) | 0.902 |
FFP | 0 (0–0) | 0 (0–0) | 0 (0–2) | 0 (0–0) | 0.329 |
TC | 0 (0–0) | 0 (0–0) | 0 (0–0) | 0 (0–0) | 0.337 |