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Fig. 2 | BMC Gastroenterology

Fig. 2

From: Expression of unfolded protein response genes in post-transplantation liver biopsies

Fig. 2

Volcano plot and pathway analysis examining hepatic gene expression in patients with hyperbilirubinemia. A Volcano plot comparing the hepatic gene expression of the NR:Mild group to the NR:HBR group. Expression of CYP7A1 was significantly higher, while LOXL4, CFTR and ADGRG2 expression was lower in the NR:Mild group. B Differentially expressed hepatic pathways in patients with hyperbilirubinemia. GSEA study using the Hallmark pathway database comparing the NR:HBR group to the NR:Mild group. C The Unfolded_Protein_Response pathway had a normalized enrichment score of 1.431951 comparing the NR:HBR group to NR:Mild group, although the FDR q-value was 0.051

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