Table 3 Summary data on variables included in prediction models in Teen Focus 4 and Focus at 24 years clinic
From: Evaluating future risk of NAFLD in adolescents: a prediction and decision curve analysis
Total number of valid CAP measurements = 3274 | Teen Focus 4 Clinic (mean age 17.8 years) | Focus@24+ Clinic (mean age 24.0 years) | |||||
|---|---|---|---|---|---|---|---|
Males | Female | Male | Female | ||||
BMI (kg/m2) | Median (IQR) | 21.7 (20.0–24.1) n = 898 | 21.9 (20.0–24.5) n = 1581 | p = 0.11 | 24.2 (21.8–26.9) n = 1176 | 23.4 (21.2–27.0) n = 2067 | p = 0.002 |
Waist circumference-to-height ratio | Median (IQR) | 0.43 (0.41–0.45) n = 737 | 0.45 (0.42–0.49) n = 1250 | p < 0.0001 | 0.47 (0.43–0.51) n = 1173 | 0.45 (0.42–0.51) n = 2061 | p < 0.0001 |
Triglycerides (< 1.7 mmol/l) | Median (IQR) | 0.7 (0.6–0.9) n = 685 | 0.7 (0.6–1.0) n = 969 | p = 0.11 | 0.9 (0.7–1.2) n = 1011 | 0.8 (0.6–1.1) n = 1647 | p < 0.0001 |
Cholesterol (< 5·2mmmol/l) | Mean (SD) | 3.6 (0.6) n = 685 | 3.9 (0.7) n = 969 | p < 0.0001 | 4.4 (0.8) n = 1012 | 4.5 (0.8) n = 1647 | p < 0.0001 |
LDL-C (mmol/l) | Mean (SD) | 2.0 (0.6) n = 685 | 2.2 (0.6) n = 969 | p < 0.0001 | 2.5 (0.8) n = 1010 | 2.4 (0.8) n = 1647 | p = 0.22 |
VLDL-C (mmol/l) | Median (IQR) | 0.3 (0.3–0.4) n = 685 | 0.3 (0.3–0.4) n = 969 | p = 0.06 | 0.4 (0.3–0.6) n = 1010 | 0.4 (0.3–0.5) n = 1647 | p < 0.0001 |
HDL-C (> 1·45 mmol/l) | Mean (SD) | 1.2 (0.3) n = 685 | 1.3 (0.3) n = 969 | p < 0.0001 | 1.4 (0.4) n = 1012 | 1.6 (0.4) n = 1647 | p < 0.0001 |
HOMA-IR (< 1·68) | Median (IQR) | 1.3 (1.0–2.0) n = 675 | 1.6 (1.1–2.2) n = 947 | p < 0.0001 | 1.8 (1.2–2.5) n = 1012 | 1.8 (1.2–2.7) n = 1647 | p = 0.04 |
Systolic blood pressure (mmHg) | Mean (SD) | 124.1 (10.1) n = 860 | 113.9 (9.1) n = 1482 | p < 0.0001 | 122.9 (10.8) n = 1179 | 111.6 (9.6) n = 2084 | p < 0.0001 |
Diastolic blood pressure (mmHg) | Mean (SD) | 63.0 (6.4) n = 860 | 64.4 (6.4) n = 1482 | p < 0.0001 | 67.6 (8.1) n = 1179 | 66.4 (7.8) n = 2084 | p = 0.0001 |
ALT (10–35 U/l) | Median (IQR) | 16.4 (12.8–21.6) n = 678 | 14.0 (11.3–17.8) n = 962 | p < 0.0001 | 26.4 (19.6–37.0) n = 1012 | 17.4 (13.7–23.3) n = 1645 | p < 0.0001 |
AST (10–35 U/l) | Median (IQR) | 20.6 (17.7–24.9) n = 678 | 18.5 (16.2–21.6) n = 962 | p < 0.0001 | 27.4 (22.8–33.1) n = 1012 | 22.6 (19.6–26.6) n = 1645 | p < 0.0001 |
GGT (< 40 U/l) | Median (IQR) | 18.0 (15.0–23.0) n = 678 | 15.0 (12.0–18.0) n = 961 | p < 0.0001 | 18.0 (14.0–26.0) n = 1012 | 14.0 (11.0–19.0) n = 1647 | p < 0.0001 |