Table 2 Subgroup analysis of diagnostic effect
Subgroup | No. studies | Sample size | Sensitivity | Specificity | Diagnostic odds ratio |
|---|---|---|---|---|---|
Value | Value | Value | |||
Country | |||||
China | 8 | 2689 | 0.77 (0.70–0.82) | 0.95 (0.93–0.97) | 63 (35–115) |
Other countries | 4 | 902 | 0.89 (0.86–0.93) | 0.93 (0.88–0.96) | 107 (61–189) |
Sample source | |||||
Blood | 5 | 1061 | 0.82 (0.58–0.94) | 0.95 (0.91–0.97) | 82 (31–217) |
Stool | 7 | 2458 | 0.83 (0.77–0.88) | 0.94 (0.90–0.96) | 77 (39–149) |
Population description | |||||
Detailed | 7 | 1787 | 0.82 (0.72–0.88) | 0.94 (0.91–0.96) | 68 (45–105) |
Undetailed | 5 | 1732 | 0.78 (0.70–0.83) | 0.96 (0.91–0.98) | 74 (26–207) |
ACTB for reference | |||||
Yes | 8 | 2735 | 0.77 (0.69–0.83) | 0.96 (0.94–0.97) | 73 (39–137) |
No | 4 | 784 | 0.88 (0.82–0.92) | 0.90 (0.87–0.93) | 67 (36–127) |
Sample size | |||||
> 250 | 5 | 2476 | 0.83 (0.77–0.88) | 0.95 (0.92–0.97) | 102 (59–178) |
< 250 | 7 | 1043 | 0.82 (0.67–0.91) | 0.92 (0.89–0.95) | 55 (27–122) |