| | |
Severe PHLF
| | |
|---|
|
Characteristics
|
All patients (n = 105)
|
No (n = 71)
|
Yes (n = 34)
|
P value
|
|
Sex, male
|
44 (41.9%)
|
34 (47.9%)
|
10 (29.4%)
|
0.073
|
|
Age, year
|
39 ± 13
|
39 ± 13
|
41 ± 12
|
0.485
|
|
BMI, kg/m2
|
22.2 ± 3.0
|
22.5 ± 3.0
|
21.6 ± 3.0
|
0.156
|
|
Positive HBsAg
|
45 (42.9%)
|
30 (42.3%)
|
15 (44.1%)
|
0.857
|
|
Serum albumin, g/L
|
35.7 ± 4.5
|
36.9 ± 3.9
|
33.2 ± 4.7
|
< 0.001
|
|
Total bilirubin, μmol/L
|
15.4 ± 13.9
|
11.6 ± 9.0
|
23.2 ± 18.4
|
< 0.001
|
|
INR
|
1.10 ± 0.21
|
1.07 ± 0.22
|
1.15 ± 0.18
|
< 0.001
|
|
Platelet count, 109/L
|
260 ± 91
|
262 ± 92
|
254 ± 90
|
0.706
|
|
Child–Pugh grade
| | | |
< 0.001
|
|
A
|
76 (72.4%)
|
62 (81.6%)
|
14 (18.4%)
| |
|
B
|
28 (26.7%)
|
9 (32.1%)
|
19 (67.9%)
| |
|
C
|
1 (0.9%)
|
0 (0%)
|
1 (100%)
| |
|
ICG-R15, %
|
6.1 ± 5.4
|
4.1 ± 3.6
|
10.3 ± 6.3
|
< 0.001
|
|
ALICE grade
| | | |
< 0.001
|
|
Grade 1
|
57 (54.3%)
|
53 (93.0%)
|
4 (7.0%)
| |
|
Grade 2
|
40 (38.1%)
|
17 (42.5%)
|
23 (57.5%)
| |
|
Grade 3
|
8 (7.6%)
|
1 (12.5%)
|
7 (87.5%)
| |
|
lesion size, cm
|
10.4 ± 5.0
|
8.9 ± 3.8
|
13.5 ± 5.9
|
< 0.001
|
|
operative time, hour
|
6.7 ± 3.1
|
5.6 ± 2.4
|
9.0 ± 3.0
|
< 0.001
|
|
Lesion number
|
0.003
|
|
Single
|
40 (38.1%)
|
34 (85.0%)
|
6 (15.0%)
| |
|
Multiple
|
65 (61.9%)
|
37 (56.9%)
|
28 (43.1%)
| |
|
Extent of hepatectomy
|
0.001
|
|
Minor resection
|
27 (25.7%)
|
25 (92.6%)
|
2 (7.4%)
| |
|
Major resection
|
78 (74.3%)
|
46 (59.0%)
|
32 (41.0%)
| |
|
Blood loss
|
< 0.001
|
|
< 500 mL
|
41 (39.0%)
|
37 (90.2%)
|
4 (9.8%)
| |
|
≥ 500 mL
|
64 (61.0%)
|
34 (53.1%)
|
30 (46.9%)
| |
- BMI Body Mass Index; INR international normalized ratio; ICG indocyanine green; ICG‐R15 ICG retention test at 15 min; ACLICE score Albumin-Indocyanine Green Evaluation score
