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Table 4 The influence of specific prognostic factors on the CSS of elderly MPM patients, based on the log-rank test

From: Clinical-pathological characteristics and prognostic factors for malignant peritoneal mesothelioma in the elderly

Variable Number Death toll Median survival time (months) 1-year CSS rate (%) 3-year CSS rate (%) 5-year CSS rate (%) P value (CSS)a
Gender        0.006
Male 391 335 5 31.46 15.73 10.88  
Female 274 214 9 43.1 22.97 14.79  
Race        0.507
White 616 511 6 36.27 18.07 1175  
black 24 16 8  
Asian or Pacific Islander 23 21 2  
American Indian/Alaska Native 2 1 7  
Insurance status         < 0.001
Insured 239 167 10 45.77 27.82 20.86  
Uninsured 3 3 1  
Unknown 423 379 5 31.20 14.23 8.75  
Marital status        0.046
Married 398 337 6 33.8 16.08 10.55  
Unmarried 256 205 7 38.77 21.47 13.99  
Unknown 11 7 15  
Site        0.936
Peritoneum 630 522 6 36.41 18.54 12.52  
Retroperitoneum 32 25 3  
Ovarlapping lesion of Retroperitoneum &peritoneum 3 2 1  
Histology         < 0.001
Epithelioid 195 147 13 50.77 26.41 19.69  
Biphasic 19 17 4  
Sarcomatoid 19 18 1  
Unknown 432 341 5 32.06 16.87 10.44  
Grade         < 0.001
Well differentiated 33 17 51  
Moderately differentiated 11 7 7  
Poorly differentiated 48 46 3  
Undifferentiated 11 9 4  
Unknown 562 470 6 36.08 18.27 12.31  
Stage         < 0.001
Localized 68 43 16 57.98 31.37 22.75  
Regional 95 78 11 46.13 27.58 18.47  
Distant 414 356 5 29.72 12.85 8.38  
Unknown 88 72 6 39.46 26.03 17.36  
Surgery         < 0.001
Cancer-directed surgery done 222 170 13 53.47 28.65 19.14  
No cancer-directed surgery 430 370 4 26.65 12.96 8.76  
Unknown 13 9 16  
Radiotherapy        0.173
Yes 15 15 6  
No/Unknown 650 534 6 36.8 19.19 12.88  
Chemotherapy        0.001
Yes 294 240 10 43.11 21.99 14.25  
No/Unknown 371 309 3 30.72 16.08 11.25  
  1. Significant P values shown in bold
  2. MPM, malignant peritoneal mesothelioma; CSS, cancer-specific survival
  3. arefers to the comparison of overall CSS until the end of follow up; “–” refers that the number of people in the corresponding group was less than 50 and survival rates were not counted