Table 4 The influence of specific prognostic factors on the CSS of elderly MPM patients, based on the log-rank test
Variable | Number | Death toll | Median survival time (months) | 1-year CSS rate (%) | 3-year CSS rate (%) | 5-year CSS rate (%) | P value (CSS)a |
|---|---|---|---|---|---|---|---|
Gender | 0.006 | ||||||
Male | 391 | 335 | 5 | 31.46 | 15.73 | 10.88 | |
Female | 274 | 214 | 9 | 43.1 | 22.97 | 14.79 | |
Race | 0.507 | ||||||
White | 616 | 511 | 6 | 36.27 | 18.07 | 1175 | |
black | 24 | 16 | 8 | – | – | – | |
Asian or Pacific Islander | 23 | 21 | 2 | – | – | – | |
American Indian/Alaska Native | 2 | 1 | 7 | – | – | – | |
Insurance status | < 0.001 | ||||||
Insured | 239 | 167 | 10 | 45.77 | 27.82 | 20.86 | |
Uninsured | 3 | 3 | 1 | – | – | – | |
Unknown | 423 | 379 | 5 | 31.20 | 14.23 | 8.75 | |
Marital status | 0.046 | ||||||
Married | 398 | 337 | 6 | 33.8 | 16.08 | 10.55 | |
Unmarried | 256 | 205 | 7 | 38.77 | 21.47 | 13.99 | |
Unknown | 11 | 7 | 15 | – | – | – | |
Site | 0.936 | ||||||
Peritoneum | 630 | 522 | 6 | 36.41 | 18.54 | 12.52 | |
Retroperitoneum | 32 | 25 | 3 | – | – | – | |
Ovarlapping lesion of Retroperitoneum &peritoneum | 3 | 2 | 1 | – | – | – | |
Histology | < 0.001 | ||||||
Epithelioid | 195 | 147 | 13 | 50.77 | 26.41 | 19.69 | |
Biphasic | 19 | 17 | 4 | – | – | – | |
Sarcomatoid | 19 | 18 | 1 | – | – | – | |
Unknown | 432 | 341 | 5 | 32.06 | 16.87 | 10.44 | |
Grade | < 0.001 | ||||||
Well differentiated | 33 | 17 | 51 | – | – | – | |
Moderately differentiated | 11 | 7 | 7 | – | – | – | |
Poorly differentiated | 48 | 46 | 3 | – | – | – | |
Undifferentiated | 11 | 9 | 4 | – | – | – | |
Unknown | 562 | 470 | 6 | 36.08 | 18.27 | 12.31 | |
Stage | < 0.001 | ||||||
Localized | 68 | 43 | 16 | 57.98 | 31.37 | 22.75 | |
Regional | 95 | 78 | 11 | 46.13 | 27.58 | 18.47 | |
Distant | 414 | 356 | 5 | 29.72 | 12.85 | 8.38 | |
Unknown | 88 | 72 | 6 | 39.46 | 26.03 | 17.36 | |
Surgery | < 0.001 | ||||||
Cancer-directed surgery done | 222 | 170 | 13 | 53.47 | 28.65 | 19.14 | |
No cancer-directed surgery | 430 | 370 | 4 | 26.65 | 12.96 | 8.76 | |
Unknown | 13 | 9 | 16 | – | – | – | |
Radiotherapy | 0.173 | ||||||
Yes | 15 | 15 | 6 | – | – | – | |
No/Unknown | 650 | 534 | 6 | 36.8 | 19.19 | 12.88 | |
Chemotherapy | 0.001 | ||||||
Yes | 294 | 240 | 10 | 43.11 | 21.99 | 14.25 | |
No/Unknown | 371 | 309 | 3 | 30.72 | 16.08 | 11.25 |