Table 3 Logistic regression analysis of the risk factors for distinguishing HCC from ICC
Variables | β | OR (95% CI) | p value |
|---|---|---|---|
Development set | |||
Sex (Male vs Female) | 1.293 | 3.645 (1.398–9.504) | 0.008 |
HBsAg (Positive vs Negative) | 1.010 | 2.747 (1.054–7.159) | 0.039 |
Cirrhosis (Yes vs No) | 1.885 | 6.590 (2.648–16.398) | < 0.001 |
MPV (fL) | 0.464 | 1.590 (1.171–2.159) | 0.003 |
AST (U/L) | 0.002 | 1.002 (1.000–1.003) | 0.018 |
AFP (ng/mL) | − 0.026 | 0.974 (0.957–0.991) | 0.003 |
CA19-9 (U/mL) | 0.067 | 1.069 (1.015–1.126) | 0.011 |
Validation set | |||
Sex (Male vs Female) | 2.669 | 14.424 (2.795–74.439) | 0.001 |
Haemoglobin (g/L) | − 0.058 | 0.944 (0.910–0.979) | 0.002 |
MPV (fL) | 1.388 | 4.007 (1.226–13.094) | 0.022 |
Total bilirubin (μmol/L) | − 0.014 | 0.986 (0.973–0.999) | 0.040 |
AFP (ng/mL) | 0.007 | 1.007 (1.002–1.012) | 0.008 |
CA19-9 (U/mL) | − 0.015 | 0.985 (0.972–0.998) | 0.020 |