Table 1 Baseline anthropometry, faecal calprotectin concentrations and urinary and plasma concentrations of iFABP
Controls (n = 28) | Established coeliac (n = 40) | Newly diagnosed coeliac (n = 12) | Crohn's disease (n = 47) | Ulcerative colitis (n = 11) | |
|---|---|---|---|---|---|
Female (%) | 10/28 (35.7%) | 23/40 (57.5%) | 8/12 (66.7%) | 13/47 (27.7%) | 4/11 (36.4%) |
Age (yrs) | 9.1 (4.6, 11.7) | 9.5 (7.2, 11.3) | 11.0 (9.2, 12.9) | 14.0 (11.2, 14.9)*** | 13.6 (11.4, 15.0)*** |
Height (m) | 1.39 (1.08, 1.51) | 1.36 (1.24, 1.48) | 1.36 (1.32, 1.56) | 1.53 (1.39, 1.64)*** | 1.59 (1.42, 1.67)** |
Height (z-score) | 0.64 (− 0.72, 1.14) | − 0.14 (− 0.66, 0.63) | 0.02 (− 0.87, 0.62) | − 0.24 (− 0.69, 0.6)* | 0.24 (− 0.51, 0.37) |
Weight (kg) | 35.15 (18.8, 47.2) | 30.0 (22.2, 43.2) | 33.5 (23.1, 40.9) | 36.5 (30.0, 49.9) | 48.4 (30.2, 62.1)** |
Weight (z-score) | 0.63 (− 0.39, 1.44) | − 0.03 (− 0.68, 0.66) | − 0.14 (− 0.82, 0.42) | − 0.74 (− 1.46, 0.35)*** | 0.62 (− 1.26, 0.89) |
BMI (kg/m2) | 16.7 (16.0, 20.3) | 16.9 (15.0, 18.7) | 17.1 (15.0, 19.0) | 16.4 (14.9, 18.6) | 18.1 (16.1, 23.4) |
BMI (z-score) | 0.35 (− 0.22, 1.19) | 0.09 (− 0.58, 0.88) | 0.06 (− 0.92, 0.64) | − 0.8 (− 1.74, 0.2)*** | 0.49 (− 1.29, 1.07) |
CRP (mg/L) | – | – | – | 9.0 (3.0, 26.5) | 3.0 (2.5, 3.0) |
TGA (U/mL) | – | 1.9 (1.1, 6.5) | 101.5 (32.8, 128.0) | – | – |
GIP (μg/g) | – | 0.16 (0.16, 0.16) | 2.67 (1.0, 5.0) | – | – |
Faecal calprotectin (mg/kg) | 5.3 (2.9, 16.4) | 22.1 (11.2, 47) | 36.5 (25.0, 57.8) | 1609 (1125, 1867)*** | 1581 (473, 1777)*** |
Urinary iFABP (pg/mg) | 51 (27, 109) | – | 26 (0, 80) | 95 (32, 161) | 38 (29, 81) |
Plasma iFABP (pg/mL) | 938 (616, 1140) | 1070 (760, 1415) | 2104 (1493, 2457)** | 1339 (895, 1969)** | 1309 (1005, 1458) |