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Table 3 Diagnostic value of mSEPT9 and FIT in CRC

From: Methylated Septin9 has moderate diagnostic value in colorectal cancer detection in Chinese population: a multicenter study

 

mSEPT9

FIT

Sensitivity

0.77 (0.70, 0.83)

0.88 (0.82, 0.92)

Specificity

0.88 (0.81, 0.93)

0.80 (0.72, 0.86)

PPV

0.88 (0.82, 0.93)

0.84 (0.78, 0.89)

NPV

0.75 (0.68, 0.82)

0.84 (0.77, 0.90)

Accuracy

0.82 (0.77, 0.85)

0.84 (0.79, 0.88)

AUC

0.82(0.78, 0.86)

0.83 (0.79, 0.88)

  1. PPV Positive predictive value; NPV Negative predictive value; AUC area under the curve