Table 1 Comparison of clinical data between CRC and non-CRC subjects

Gender

 Male

211 (64.7%)

113 (62.8%)

98 (67.1%)

 Female

115 (35.3%)

67 (37.2%)

48 (32.9%)

Age (years)

58.6 ± 10.1

59.5 ± 9.62

57.5 ± 10.5

Histological type

 No

320 (98.2%)

177 (98.3%)

143 (97.9%)

 Yes

6 (1.84%)

3 (1.67%)

3 (2.05%)

Diabetes mellitus

 No

303 (92.9%)

165 (91.7%)

138 (94.5%)

 Yes

23 (7.06%)

15 (8.33%)

8 (5.48%)

Hypertension

 No

252 (77.3%)

137 (76.1%)

115 (78.8%)

 Yes

74 (22.7%)

43 (23.9%)

31 (21.2%)

Hyperlipidemia

 No

260 (79.8%)

134 (74.4%)

126 (86.3%)

 Yes

66 (20.2%)

46 (25.6%)

20 (13.7%)

Smoking

 No

244 (74.8%)

115 (63.9%)

129 (88.4%)

 Yes

82 (25.2%)

65 (36.1%)

17 (11.6%)

Alcohol

 No

261 (80.1%)

138 (76.7%)

123 (84.2%)

 Yes

65 (19.9%)

42 (23.3%)

23 (15.8%)

Location

 Colon

209 (64.1%)

90 (50.3%)

119 (81.0%)

 Rectal

117 (35.9%)

89 (49.7%)

28 (19.0%)

Lesion size (cm)

2.44 ± 1.93

3.13 ± 1.99

1.07 ± 0.67)

Histological type

 Adenocarcinoma

179 (54.9%)

 Polyp

97 (29.8%)

 Adenoma

37 (11.3%)

 Inflammation

12 (3.68%)

 Normal

1 (0.31%)

Hemoglobin (g/L)

125 ± 21.3

119 ± 22.0

135 ± 16.4

Platelet (×10⁹)

273 ± 90.2

296 ± 96.7

242 ± 69.2

Neutrophil (×10⁹)

5.01 ± 12.1

5.68 ± 15.8

4.10 ± 2.01

lymphocyte (×10⁹)

1.87 ± 0.66

1.88 ± 0.71

1.85 ± 0.60

Albumin (g/L)

39.4 ± 5.32

37.5 ± 5.04

42.2 ± 4.49

CEA (ng/mL)

48.0 ± 280

78.5 ± 360

3.03 ± 3.64

AFP (ng/mL)

2.92 ± 2.02

2.97 ± 2.42

2.83 ± 1.24

CA125 (U/mL)

18.6 ± 50.7

22.8 ± 62.6

11.1 ± 9.15

CA153 (U/mL)

10.3 ± 6.62

10.2 ± 7.27

10.5 ± 5.36

CA199 (U/mL)

147 ± 993

239 ± 1275

9.95 ± 9.34

FIT

 Positive

187 (57.4%)

157 (87.7%)

30 (20.4%)

 Negative

139 (42.6%)

22 (12.3%)

117 (79.6%)

mSEPT9

 Positive

155 (47.5%)

137 (76.5%)

18 (12.2%)

 Negative

171 (52.5%)

42 (23.5%)

129 (87.8%)