Variables | Elderly patients | Younger patients | P-value (p < 0.05) |
---|---|---|---|
Age | 72.9 \(\pm\) 6.1 | 48.7 \(\pm\) 12.2 | – |
Sex (male/female) | 350:180 | 573:157 | < 0.01 |
Comorbidity | |||
Cirrhosis | 52 (9.8%) | 108(14.8%) | < 0.01 |
Renal failure | 56 (10.6%) | 10(1.4%) | < 0.01 |
Any malignancy | 46 (8.7%) | 118(16.2%) | < 0.01 |
PCI | 52 (9.8%) | 28(3.8%) | < 0.01 |
Heart failure | 16 (3.0%) | 2(0.3%) | < 0.01 |
Hypertension | 294 (55.5%) | 212(29%) | < 0.01 |
Diabetes | 102 (19.2%) | 90(12.3%) | < 0.01 |
Chronic lung disease | 18 (3.4%) | 2(0.3%) | < 0.01 |
Medications | |||
NSAIDs | 6 (1.1%) | 4(0.5%) | > 0.05 |
Aspirin | 130 (24.5%) | 62(8.5%) | < 0.01 |
Clopidogrel | 64 (12.1%) | 20(2.7%) | < 0.01 |
Oral anticoagulants | 22 (4.2%) | 4(0.5%) | < 0.01 |
Steroids | 8 (1.5%) | 6(0.8%) | > 0.05 |
Relevant variables and scores components (median (IQR)) | |||
Systolic blood pressure(mmHg) | 124(28) | 120(24) | – |
Pulse(beats/min) | 79(18) | 82(22.5) | – |
Creatinine(μmol/L) | 82(41) | 73(27) | – |
Hemoglobin(g/L) | 89(43) | 102.5(45) | – |
Albumin (g/L) | 33.7(8.45) | 37.25(9.08) | – |
Urea(mmol/L) | 9.7(10.1) | 7.9(6.35) | – |
ASA score | 3(1) | 2(2) | – |
Findings at endoscopy | |||
Duodenal/gastric ulcer | 246 (46.4%) | 424(58%) | < 0.01 |
Erosions | 44 (8.3%) | 56(7.7%) | > 0.05 |
Upper GI cancer | 70 (13.2%) | 28(3.8%) | < 0.01 |
Variceal bleeding | 44 (8.3%) | 88(12.1%) | < 0.05 |
Esophagitis | 16 (3.0%) | 10(1.4%) | < 0.05 |
Mallory-Weiss syndrome | 16 (3.0%) | 32(4.4%) | > 0.05 |
Normal | 94(16.9%) | 92(12.3%) | < 0.05 |
Outcomes | |||
Death (total) | 44 (8.3%) | 24(3.3%) | < 0.01 |
Intervention | 240 (45.3%) | 304 (41.6%) | > 0.05 |
Rebleeding | 112 (21.1%) | 60 (8.2%) | < 0.01 |