Fig. 2

Selected examples of ontologically related genes in GIT. Heatmaps for organ specific (green columns, top) and general genes (orange columns, top) that are annotated simultaneously by ontology terms GO:0018193: peptidyl-amino acid modification and GO:0042326: negative regulation of phosphorylation (a), GO:0045309: protein phosphorylated amino acid binding and GO:0044267: cellular protein metabolic process (c), and GO:0045309: protein phosphorylated amino acid binding and PW:0000417: ubiquitin, ubiquitin like/proteasome degradation pathway (e). Schematic visualization of gene ontology and their more general terms for GO:0018193 and GO:0042326 (b), GO:0045309 and GO:0044267 (d), GO:0045309 and PW:0000417 (f). We note that these terms are highlighted by yellow color. Selected ontologies illustrate the ability of semantical clustering to group genes that carry the same biological function in different parts of the organ. Scheme shows the relationships among ontology terms related to biological processes that might help the analyst to orient in such extensive ontologies and then interpret the meaning of terms easier