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Table 3 Cox regression analysis of prognostic factors for 5-year survival in hepatocellular carcinoma

From: Nuclear respiratory factor 1 promotes the growth of liver hepatocellular carcinoma cells via E2F1 transcriptional activation

  Univariate analysis Multivariate analysis
P HR 95% CI P HR 95% CI
Gender 0.742 0.91 0.53–1.58    
 Male vs Female       
Age 0.227 0.73 0.43–1.22    
 < 55 vs ≥ 55       
Grade 0.801 1.08 0.61–1.91    
 Well and moderate vs poor       
Vessel invasion 0.208 1.36 0.84–2.21    
 No vs yes       
TNM 0.052 1.40 1.00–1.97    
 I vs II and III       
Tumor size 0.071 1.56 0.96–2.51    
 ≤ 5 cm vs > 5 cm       
Cirrhosis 0.018* 1.98 1.13–3.47 0.057 1.74 0.98–3.09
 No vs yes       
NRF1 0.004** 2.05 1.26–3.34 0.013* 1.87 1.14–3.06
 Low vs high       
  1. *P < 0.05, **P < 0.01