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Table 8 Univariate and multivariate analyses for predicting grade ≥ 3 intra-abdominal infection

From: Comparison of operative outcomes between monopolar and bipolar coagulation in hepatectomy: a propensity score-matched analysis in a single center

Variables

Grade ≥ 3 intra-abdominal infection

Multivariate analysis

Yes (n = 11)

No (n = 135)

P value

OR

95% CI

P value

Age

68 (37–84, 12)

70 (31–87, 15)

0.439

   

Sex (male/female)

9/2

94/41

0.402

   

BMI

24.7 (18.8–27.3, 7.4)

22.4 (15.4–37.1, 4.2)

0.368

   

ASA (1 or 2/3)

10/1

114/21

0.570

   

Diagnosis (HCC/non-HCC)

4/7

83/52

0.115

   

Background liver condition (hepatitis/normal)

4/7

77/58

0.195

   

Type of resection (major hepatectomya/minor hepatectomyb)

10/1

99/36

0.226

   

Number of resected lesions

1 (1–2, 0)

1 (1–16, 0)

0.494

   

Size of the largest nodule on preoperative imagingc (cm)

2.3 (1.2–5.0, 2.1)

2.5 (0.5–20.0, 2.1)

0.435

   

Number of nodules on preoperative imagingc

1 (1–10, 1)

1 (1–10, 1)

0.577

   

Lymph node dissection (yes/no)

5/6

15/120

0.004

8.661

1.985–37.794

0.004

Biliary reconstruction (yes/no)

2/9

9/126

0.184

   

Neoadjuvant chemotherapy (yes/no or previous)

2/9

19/116

0.710

   

Total bilirubin (mg/dL) (≥ 1.1/ < 1.1)

3/8

30/105

0.701

   

Aspartate transaminase (IU/L) (≥ 31/ < 31)

2/9

72/63

0.041

0.151

0.028–0.823

0.029

Albumin (g/dL) (≥ 3.9/ < 3.9)

9/2

85/50

0.225

   

Prothrombin activity (%) (≥ 69/ < 69)

11/0

129/6

0.999

   

Activated partial thromboplastin time (%) (≥ 69/ < 69)

8/3

119/16

0.159

   

Hemoglobin (g/dL) (≥ 11.4/ < 11.4)

10/1

107/28

0.369

   

Platelet (× 104/μL) (≥ 15.3/ < 15.3)

9/2

79/56

0.148

   

Blood urea nitrogen (mg/dL) (≥ 20.0/ < 20.0)

1/10

20/115

0.607

   

Creatinine (mg/dL) (≥ 1.07/ < 1.07)

2/9

21/114

0.818

   

C-reactive proteind (mg/dL) (≥ 0.14/ < 0.14)

2/9

48/69

0.156

   

ICGR15e (%) (≥ 10/ < 10)

4/6

86/44

0.213

   

Child–Pugh score

5 (5–5, 0)

5 (5–8, 0)

0.998

   

Total operative time (min)

318 (202–438, 167)

251 (74–673, 119)

0.244

   

Transection timef (min)

89 (50–223, 63)

84 (15–298, 67)

0.494

   

Pringle maneuverg (min)

61 (41–119, 50)

56 (15–159, 32)

0.286

   

Blood loss (mL)

470 (120–1365, 425)

565 (0–8030, 676)

0.321

   

Red blood cell transfusion (mL)

0 (0–0, 0)

0 (0–3360, 0)

0.996

   

Hemostatic device (monopolar/bipolar)

9/2

64/71

0.045

5.905

1.096–31.825

0.039

  1. Continuous data are presented as median (range, interquartile range), whereas categorical data are shown as number of patients. Significant P-values are in boldface
  2. BMI, body mass index; ASA, American Society of Anesthesiologists; HCC, hepatocellular carcinoma; ICGR15, indocyanine green retention rate at 15 min; OR, odds ratio; CI, confidence interval
  3. aMajor hepatectomy indicates more than one section hepatectomy excluding left lateral hepatectomy
  4. bMinor hepatectomy indicates partial and left lateral hepatectomy
  5. cData on the size of the largest nodule and number of nodules were partially lacking because biliary tract cancer and benign disease could not be accurately measured (with ascites, 8 cases; without ascites, 126 cases)
  6. dData on C-reactive protein were partially lacking (with ascites, 11 cases; without ascites, 117 cases)
  7. eData on ICGR15 were partially lacking (with ascites, 10 cases; without ascites, 130 cases)
  8. fData on total transection time were partially lacking (with ascites, 11 cases; without ascites, 115 cases)
  9. gData on total Pringle maneuver time were partially lacking (with ascites, 9 cases; without ascites, 90 cases)
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BMC Gastroenterology

ISSN: 1471-230X

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