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Fig. 5 | BMC Gastroenterology

Fig. 5

From: CD63-positive extracellular vesicles are potential diagnostic biomarkers of pancreatic ductal adenocarcinoma

Fig. 5

Combined use of CD63+-EVs and CA19-9 for detection of early-stage PDAC. The values of CD63+-EVs × CA19-9 were calculated by multiplying the OD values of CD63+-EVs and CA19-9 level. The values of CD63+-EVs × CA19-9 in HCs (n = 39) and PDACs (n = 39) (a) or early-stage PDACs (stage I–II, n = 23) (b) were shown. p-values obtained by Wilcoxon–Mann–Whitney Test are indicated in the figure. (c) Comparison of ROC curve of CA19-9 and CD63+-EVs × CA19-9 in early-stage sets consisting of 39 HCs and 23 early-stage PDAC. Solid and dotted line indicates CD63+-EVs × CA19-9 and CA19-9, respectively. p-values obtained by DeLong’s test are indicated in the figure

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BMC Gastroenterology

ISSN: 1471-230X

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