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Table 5 Faecal calprotectin levels in different stages of colorectal cancer

From: The role of faecal calprotectin in diagnosis and staging of colorectal neoplasia: a systematic review and meta-analysis

Author

Year

CRC total n

Stage

Comment

0/I

II

III

IV

n (%)

n (%)

n (%)

n (%)

FC (Median)

FC (Median)

FC (Median)

FC (Median)

Gilbert

1996

14

 

5 (36.0)

2 (14.0)

7 (50.0)

Stage had no effect on faecal calprotectin levels

Kristinsson

1998

119

25 (21.0)

33 (28.0)

36 (30.0)

25 (21.0)

No significant difference

   

50 mg/l

65 mg/l

34 mg/l

38 mg/l

 

Kristinsson

2001

155

20 (13.0)

66 (43.0)

45 (29.0)

23 (15.0)

No significant difference

   

27 mg/l

49 mg/l

42 mg/l

48 mg/l

 

Tibble

2001

62

10 (16.0)

24 (39.0)

14 (23.0)

14 (23.0)

No significant difference (p > 0.2)

   

62.5 mg/l

115 mg/l

62 mg/l

132 mg/l

 

Karl

2008

85 (186)

23 (27.0)

27 (32.0)

12 (14.0)

23 (27.0)

85/186 CRC had stage specified

   

179.2 μg/g

550.2 μg/g

542.5 μg/g

312.8 μg/g

 

Kalimutho

2011

28

7

5

3

 

18 CRC either did not have FC or stage data

   

4/7+ve FC

3/5+ve FC

3/3+ve FC

  

Lehman

2014

80

    

Patients with T3/4 disease had significantly higher FC than T1/2 (p = 0.022)

  1. CRC colorectal cancer, FC faecal calprotectin