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Fig. 6 | BMC Gastroenterology

Fig. 6

From: RIP3 knockdown inhibits necroptosis of human intestinal epithelial cells via TLR4/MyD88/NF-κB signaling and ameliorates murine colitis

Fig. 6

Knockdown of RIP3 expression inhibits inflammatory signaling pathways in vivo. A Immunohistochemistry detected the expression and distribution of CD68 in the mouse colon. Scale bar: 50 μm. B The mean optical density value (IOD) of CD68 protein in each field was analyzed by Image-Pro Plus 6.0 software. C Western blot detected the effect of RIP3 knockout or knockdown in vivo on key molecules of TLR4/NF-κB signaling pathway. D–F The levels of D SOD, E MDA and F MPO in the mouse colon collected after 7 days’ administration

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BMC Gastroenterology

ISSN: 1471-230X

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