Effect of alcohol on clinical complications of hepatitis virus-induced liver cirrhosis: a consecutive ten-year study

Table 2 Proportion of cirrhosis complications in the studied groups

Complications	ALD n (%)	HBV n (%)	HCV n (%)	ALD + HBV n (%)	ALD + HCV n (%)	P value
HCC	170 (10.3)	7622 (42.2)^a	142 (20.8)^a,b,d	832 (52.2)^a,b	96 (34.3)^a,c,d	< 0.001
Infection	553 (33.5)	4184 (23.1)^a	129 (18.9)^a,d	486 (30.5)^b	79 (28.2)^c	< 0.001
Ascites	892 (54.0)	7835 (43.3)^a	252 (37.0)^a,b,d	879 (55.1)^b	144 (51.4)^c	< 0.001
HE	127 (7.7)	947 (5.2)^a	20 (2.9)^a,d	104 (6.5)	14 (5.0)	< 0.001
Thrombus	102 (6.2)	1040 (5.8)	35 (5.1)	80 (5.0)	12 (4.3)	0.461
EGV^†	813 (49.6)	6612 (38.3)^a	266 (41.1)^b	707 (45.5)^a,b	129 (46.1)^b	0.001
EGVB^‡	318 (39.1)	1990 (30.1)^a	87 (32.7)	306 (43.3)^b	66 (51.2)^c	< 0.001
HRS	49 (3.0)	276 (1.5)^a	8 (1.2)	35 (2.2)	3 (1.1)	< 0.001

HCC, hepatocellular carcinoma; HE, hepatic encephalopathy; EGV, esophageal gastric varices; EGVB, esophageal gastric variceal bleeding, HRS, hepatorenal syndrome
^aMeans value statistically significant compared to that in ALD; ^bmeans value statistically significant compared to that in HBV; ^cmeans value statistically significant compared to that in HCV; ^dmeans value statistically significant compared to that in HBV + ALD. Bonferroni correction was used for “P” during pairwise comparisons
^†The proportion of EGV was calculated by dividing the number of patients reported with EGV by the number of patients who underwent upper GI endoscopy or other imaging examination such as CT or MR, capable of detecting EGV; ^‡The proportion of EGVB was calculated by dividing number of patients reported with EGVB by the number of confirmed EGV patients

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