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Table 1 Demographics and symptom severities of patients undergoing high resolution esophageal manometry with impedance testing and ambulatory pH reflux monitoring for upper GI symptoms, including all patients and patients stratified by presence or absence of pathologic reflux on HREMI

From: Characterizing reflux on high resolution esophageal manometry with impedance

 

All patients (n = 229)

Patients with reflux on HREMI (n = 47)

Patients without reflux on HREMI (n = 182)

p value

Demographics

Age

56.4 ± 1.0

57.5 ± 1.5

56.1 ± 0.9

0.770

Gender (females)

156 (68.1%)

35 (74.5%)

121 (66.5%)

0.295

BMI (kg/m2)

28.7 ± 0.5

33.3 ± 1.5

27.4 ± 0.4

0.001

Upper Gastrointestinal Symptom

Heartburn

1.4 ± 0.1

1.4 ± 0.2

1.4 ± 0.1

0.809

Chest Pain

0.8 ± 0.1

0.8 ± 0.2

0.9 ± 0.1

0.845

Dysphagia

0.9 ± 0.1

0.8 ± 0.1

1.0 ± 0.1

0.434

Regurgitation

1.1 ± 0.1

0.8 ± 0.1

1.2 ± 0.1

0.033

Hoarseness

0.7 ± 0.1

0.5 ± 0.1

0.7 ± 0.1

0.087

Coughing

1.4 ± 0.1

1.3 ± 0.2

1.4 ± 0.1

0.699

Belching

0.9 ± 0.1

0.7 ± 0.1

1.0 ± 0.1

0.181

Nausea

1.1 ± 0.1

0.9 ± 0.1

1.1 ± 0.1

0.671

Vomiting

0.7 ± 0.1

0.4 ± 0.1

0.8 ± 0.1

0.169

Overall symptom severity

8.1 ± 0.4

6.9 ± 0.8

8.5 ± 0.4

0.139

Duration of symptoms (years)

7.1 ± 0.7

6.0 ± 1.1

7.4 ± 8.5

0.442

  1. Results expressed as % (n) or mean ± standard error of mean as appropriate; p value (comparing patients with reflux on HREMI to patients without reflux on HREMI) calculated using Mann Whitney U test, Student’s t test or Chi Squared test as appropriate. Overall symptom severity calculated by adding severities of individual 9 symptom scores (range 0 to 36). Abbreviations: BMI (Body Mass Index), HREMI (High Resolution Esophageal Manometry with Impedance)