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Table 3 Laboratory characteristics of patients with moderate COVID-19 on admission

From: Early changes in laboratory tests predict liver function damage in patients with moderate coronavirus disease 2019: a retrospective multicenter study

Analytes

Training set (n = 70)

Validation set (n = 31)

All patients

Liver function damage group

Normal liver function group

All patients

Liver function damage group

Normal liver function group

n

M/\(\overline{x }\)

n

M/\(\overline{x }\)

n

M/\(\overline{x }\)

n

M/\(\overline{x }\)

n

M/\(\overline{x }\)

n

M/\(\overline{x }\)

Liver function parameters

TP

70

69.50

45

69.22*

25

71.25

22

68.71

12

65.58*

10

73.14

ALB

70

40.49

45

38.15*

25

42.00

22

39.55

12

35.94*

10

43.87

ALT

70

25.00

45

31.00*

25

19.00

31

19.70

21

16.00*

10

24.00

AST

70

26.00

45

28.00*

25

21.00

31

22.00

21

22.00

10

23.50

ALP

59

70.73

34

68.32

25

74.00

22

60.87

12

60.51

10

61.30

GGT

70

59.00

45

75.00*

25

19.00

31

68.00

21

70.00*

10

24.50

TBIL

70

9.50

45

8.30*

25

11.40

31

9.60

21

8.00*

10

14.50

Kidney function parameters

Glu

70

6.36

45

6.39

25

6.17

31

6.17

21

6.59

10

5.65

Cr

70

67.35

45

67.21

25

67.61

31

65.69

21

65.00

10

67.14

Ur

70

3.69

45

3.65

25

4.02

31

4.17

21

4.17

10

3.96

CO2-CP

70

24.49

45

23.93*

25

25.48

31

24.37

21

22.83*

10

26.90

UA

54

279.25

32

238.05

22

290.50

15

259.63

11

259.19

4

260.83

RBP

53

31.55

31

28.72*

22

35.5

15

29.64

11

27.91

4

34.41

Platelet parameters

PLT

70

189.50

45

188.00

25

194.00

31

186.84

21

179.10

10

203.10

PDW

70

12.35

45

12.11

25

12.77

31

13.24

21

12.37*

10

15.06

PCT

48

12.48

26

10.94*

22

14.29

27

13.36

17

13.22

10

13.59

MPV

70

10.38

45

10.35

25

10.43

31

9.96

21

10.0

10

9.7

Erythrocyte parameters

RBC

70

4.53

45

4.48

25

4.63

31

4.44

21

4.27*

10

4.81

HCT

70

0.41

45

0.40

25

0.41

31

0.40

21

0.39*

10

0.43

HGB

70

139.05

45

138.24

25

140.52

31

138.07

21

132.90*

10

148.92

MCV

70

89.50

45

89.60

25

89.50

31

90.77

21

90.68

10

90.96

MCH

70

30.50

45

30.50

25

30.50

31

31.14

21

31.13

10

31.16

MCHC

70

342.00

45

342.00

25

341.00

31

343.32

21

343.57

10

342.80

RDW

70

11.95

45

11.90

25

12.10

31

11.9

21

12.08

10

11.69

Leukocyte parameters

WBC

70

5.51

45

5.69

25

5.18

31

5.01

21

5.04

10

4.93

NE#

70

3.31

45

3.40

25

2.60

31

3.19

21

3.16

10

3.25

NE%

70

61.73

45

62.49

25

60.37

31

62.40

21

63.10

10

61.60

LY#

70

1.46

45

1.46

25

1.44

31

1.33

21

1.39

10

1.19

LY%

70

28.01

45

27.80

25

28.40

31

27.30

21

27.60

10

23.95

MO#

70

0.40

45

0.40

25

0.50

31

0.50

21

0.32

10

0.50

MO%

70

9.02

45

8.45*

25

10.06

31

8.42

21

7.58*

10

10.20

Coagulation parameters

APTT

47

32.70

28

32.75

19

32.70

17

35.80

14

35.95

3

33.70

TT

47

15.15

28

15.08

19

15.26

17

15.49

14

15.61

3

14.93

PT

47

13.37

28

13.04*

19

13.86

17

12.64

14

12.46

3

13.47

INR

47

1.03

28

1.02

19

1.05

17

1.04

14

1.04

3

1.03

FBG

47

3.03

28

3.21

19

2.86

17

3.13

14

3.06

3

3.48

Electrolyte parameters

Na

64

139.51

41

139.13

23

140.17

28

139.05

19

139.82

9

137.43

K

64

4.02

41

4.03

23

4.00

28

4.05

19

4.00

9

4.17

Cl

64

102.12

41

101.42*

23

103.35

28

100.58

19

101.04

9

99.61

Ca

48

9.82

28

9.62*

20

10.09

13

9.58

10

9.44

3

9.98

Blood lipid parameters

TG

55

1.16

33

1.19

22

1.15

15

1.01

11

1.05

4

0.97

CHO

55

3.91

33

3.79

22

4.09

15

3.78

11

3.76

4

3.84

HDL-C

55

0.84

33

0.80*

22

0.90

15

0.85

11

0.85

4

0.86

LDL-C

54

2.00

32

1.96

22

2.06

15

1.90

11

1.91

4

1.88

Cardiac markers parameters

hsCRP

52

8.25

31

14.70*

21

6.01

24

11.92

17

20.79

7

6.00

CK

42

78.00

26

90.00

16

72.50

25

66.00

16

65.50

9

67.00

CK-MB

56

13.00

35

14.00

21

12.00

29

12.00

19

13.00

10

12.00

LDH

42

193.00

26

206.00*

16

182.00

25

213.24

16

216.81

9

206.89

  1. TP, Total protein, g/L; ALB, Albumin, g/L; ALT, Alanine aminotransferase, U/L; AST, Aspartate aminotransferase, U/L; ALP, Alkaline phosphatase, U/L; GGT, γ-glutamyl transpeptidase, U/L; TBIL, Total bilirubin, μmol/L; Glu, Glucose, mol/L; Cr, Creatinine, μmol/L; Ur, Urea, mmol/L; CO2-CP, Carbon dioxide combining power, mmol/L; UA, Uric acid, μmol/L; RBP, Retinol-binding protein, mg/L; PLT, Platelet count, × 109/L; PDW, Platelet distribution width, %; PCT, Plateletcrit, ‱; MPV, Mean platelet volume, fL; RBC, Red blood cell, × 1012/L; HCT, Hematocrit, L/L; HGB, Hemoglobin, g/L; MCV, Mean corpuscular volume, fL; MCH, Mean corpuscular hemoglobin, pg; MCHC, Mean corpuscular hemoglobin concentration, g/L; RDW, Red blood cell distribution width, %; WBC, White blood cell, × 109/L; NE#, Neutrophil count, × 109/L; NE%, Neutrophil percentage, %; LY#, Lymphocyte count, × 109/L; LY%, Lymphocyte percentage, %; MO#, Monocyte count, × 109/L; MO%, Monocyte percentage, %; APTT, Activated partial thromboplastin time, s; TT, Thrombin time, s; PT, Prothrombin time, s; INR, International normalized ratio; FBG, Fibrinogen, g/L; Na, Sodium, mmol/L; K, Potassium, mmol/L; Cl, Chloride, mmol/L; Ca, Calcium, mg/dL; TG, Triglyceride, mmol/L; CHO, Cholesterol, mmol/L; HDL-C, High-density lipoprotein cholesterol, mmol/L; LDL-C, Low-density lipoprotein cholesterol, mmol/L; hsCRP, High-sensitivity C-reactive protein, mg/L; CK, Creatine kinase, U/L; CK-MB, Creatinine kinase-muscle/brain activity, U/L; LDH, Lactate dehydrogenase, U/L. COVID-19: coronavirus disease 2019.\(\overline{x }\): Average. M: Median. The bold fonts represent the median
  2. *: Significant difference between the liver function damage group and the normal liver function group, P < 0.05
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BMC Gastroenterology

ISSN: 1471-230X

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