Table 4 Serum ceruloplasmin levels in WD children carrying R778L mutation
From: Assessment of the diagnostic value of serum ceruloplasmin for Wilson’s disease in children
Genotype | Age (years) | Cp (mg/dL) | No. of patients | |||||
|---|---|---|---|---|---|---|---|---|
Total | 0–5 | 5–10 | 10–15 | 15–20 | ≥ 20 | |||
R778L homozygotes | 5.7 ± 3.1 | 2.3 ± 0.5* | 9 | 9 | 0 | 0 | 0 | 0 |
R778L heterozygotes | 6.2 ± 3.0 | 5.2 ± 4.5 | 97 | 64 | 21 | 6 | 3 | 3 |
No R778L | 6.1 ± 2.8 | 6.1 ± 4.8 | 207 | 108 | 57 | 29 | 10 | 3 |
Total | 6.1 ± 2.9 | 5.7 ± 4.7 | 313 | 181 | 78 | 35 | 13 | 6 |