Elevated average maximum intrabolus pressure on high-resolution manometry is associated with esophageal dysmotility and delayed esophageal emptying on timed barium esophagram

Table 2 Manometry data

Manometry data	Cases	Controls	p-value
Number (N)	114	41
Mean LES RBP (mmHg)**			0.19
Normal, N (%)	53 (46.5%)	24 (58.5%)
Abnormal, N (%)	61 (53.5%)	17 (41.5%)
Mean ± SD	45.7 (21.2%)	34.5 ± 17.1	0.48
Mean LES RP (mmHg)^			< 0.001
Normal, N (%)	23 (20.2%)	23 (56.1%)
Abnormal, N (%)	91 (79.8%)	18 (43.9%)
Mean ± SD	22.3 ± 11.0	13.3 ± 7.5	0.48
DCI (mmHg-cm-s)^o			0.05
Normal, N (%)	76 (66.7%)	34 (82.9%)
Abnormal, N (%)	38 (33.3%)	7 (17.1%)
Mean ± SD	3708.8 ± 3952.9	2116.5 ± 2079.3	0.33
LES IBP (mmHg)^x			< 0.001
Normal, N (%)	55 (48.2%)	35 (85.4%)
Abnormal, N (%)	59 (51.8%)	6 (14.6%)
Mean ± SD	7.4 ± 7.1	3.0 ± 4.6	0.44
LES AVG MAX (mmHg)^z			0.95
Normal, N (%)	N/A	41
Abnormal, N (%)	114	N/A
Mean ± SD	22.6 ± 12.4	12.7 ± 3.1
Incomplete bolus clearance			0.002
Normal, N (%)	49 (43.4%)	29 (70.7%)
Abnormal, N (%)	64 (56.6%)	12 (29.3%)
Manometry			< 0.001
Normal, N (%)	5 (4.4%)	12 (29.3%)
Abnormal, N (%)	109 (95.6%)	29 (70.7%)

Normal HRM on TBE was defined as column height < 17 mmHg, as measured from gastroesophageal junction to the height of the top of the column
*BMI: body mass index
**Mean lower esophageal sphincter respiratory basal pressure
^Mean lower esophageal sphincter residual pressure
^oDistal contractile integral
^xLower esophageal sphincter intrabolus pressure
^zAverage maximum lower esophageal sphincter pressure in mmHg

ISSN: 1471-230X