Nomogram to predict cause-specific mortality of patients with rectal adenocarcinoma undergoing surgery: a competing risk analysis

Table 3 Proportional subdistribution hazards models for rectal adenocarcinoma undergoing surgery

Variables	Classification	Cause-specific death				Death due to other causes
Variables	Classification	Coefficient	HR	95% CI	P value	Coefficient	HR	95% CI	P value
Age
	< 65	Reference				Reference
	≥ 65	0.383	1.467	1.388–1.550	< 0.001	1.315	3.723	3.402–4.075	< 0.001
Race
	Black	Reference				Reference
	White	− 0.208	0.812	0.739–0.893	< 0.001	− 0.072	0.931	0.802–1.080	0.346
	Other	− 0.249	0.779	0.690–0.880	< 0.001	− 0.264	0.768	0.632–0.933	0.008
MS
	Married	Reference				Reference
	Unmarried	0.277	1.319	1.249–1.392	< 0.001	0.248	1.281	1.184–1.387	< 0.001
AJCC
	I	Reference				Reference
	II	0.723	2.060	1.838–2.309	< 0.001	0.107	1.113	1.000–1.239	0.050
	III	0.748	2.113	1.845–2.420	< 0.001	− 0.083	0.920	0.771–1.099	0.357
	IV	2.044	7.720	6.700–8.895	< 0.001	− 0.585	0.557	0.438–0.708	< 0.001
TS
	< 4 cm	Reference				Reference
	4–8 cm	0.068	1.071	1.011–1.134	0.020	0.160	1.173	1.080–1.274	< 0.001
	≥ 8 cm	0.312	1.366	1.240–1.505	< 0.001	0.104	1.110	0.939–1.313	0.223
LN
	0	Reference				Reference
	1–3	0.542	1.719	1.564–1.889	< 0.001	− 0.023	0.977	0.825–1.158	0.791
	4–8	0.886	2.426	2.190–2.686	< 0.001	− 0.020	0.980	0.804–1.194	0.841
	> 8	1.196	3.305	2.927–3.733	< 0.001	− 0.355	0.701	0.522–0.942	0.019
Radiation
	None	Reference				Reference
	Yes	− 0.035	0.965	0.895–1.041	0.357	− 0.053	0.948	0.831–1.081	0.425
Chemotherapy
	None	Reference				Reference
	Yes	− 0.211	0.810	0.741–0.885	< 0.001	− 0.534	0.586	0.514–0.669	< 0.001

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