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Table 3 Proportional subdistribution hazards models for rectal adenocarcinoma undergoing surgery

From: Nomogram to predict cause-specific mortality of patients with rectal adenocarcinoma undergoing surgery: a competing risk analysis

Variables Classification Cause-specific death Death due to other causes
Coefficient HR 95% CI P value Coefficient HR 95% CI P value
Age          
  < 65 Reference Reference
   ≥ 65 0.383 1.467 1.388–1.550 < 0.001 1.315 3.723 3.402–4.075 < 0.001
Race          
  Black Reference Reference
  White − 0.208 0.812 0.739–0.893 < 0.001 − 0.072 0.931 0.802–1.080 0.346
  Other − 0.249 0.779 0.690–0.880 < 0.001 − 0.264 0.768 0.632–0.933 0.008
MS          
  Married Reference Reference
  Unmarried 0.277 1.319 1.249–1.392 < 0.001 0.248 1.281 1.184–1.387 < 0.001
AJCC          
  I Reference Reference
  II 0.723 2.060 1.838–2.309 < 0.001 0.107 1.113 1.000–1.239 0.050
  III 0.748 2.113 1.845–2.420 < 0.001 − 0.083 0.920 0.771–1.099 0.357
  IV 2.044 7.720 6.700–8.895 < 0.001 − 0.585 0.557 0.438–0.708 < 0.001
TS          
  < 4 cm Reference Reference
  4–8 cm 0.068 1.071 1.011–1.134 0.020 0.160 1.173 1.080–1.274 < 0.001
   ≥ 8 cm 0.312 1.366 1.240–1.505 < 0.001 0.104 1.110 0.939–1.313 0.223
LN          
  0 Reference Reference
  1–3 0.542 1.719 1.564–1.889 < 0.001 − 0.023 0.977 0.825–1.158 0.791
  4–8 0.886 2.426 2.190–2.686 < 0.001 − 0.020 0.980 0.804–1.194 0.841
  > 8 1.196 3.305 2.927–3.733 < 0.001 − 0.355 0.701 0.522–0.942 0.019
Radiation          
  None Reference Reference
  Yes − 0.035 0.965 0.895–1.041 0.357 − 0.053 0.948 0.831–1.081 0.425
Chemotherapy          
  None Reference Reference
  Yes − 0.211 0.810 0.741–0.885 < 0.001 − 0.534 0.586 0.514–0.669 < 0.001
  1. MS, marital status; TS, tumor size; LN, number of metastasis lymph nodes