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Table 4 Changes of LSM values in different grades of inflammation within the same fibrosis stage

From: Diagnostic efficacy of FibroScan for liver inflammation in patients with chronic hepatitis B: a single-center study with 1185 liver biopsies as controls

S, n = 1185

G, n = 1185

G1 (LSM)

G2 (LSM)

G3 (LSM)

G4 (LSM)

S0 (56)

42 (7.31 ± 2.37)

13 (8.05 ± 2.28)

1 (5.6)

0

S1 (243)

64 (7.99 ± 2.54)

164 (8.22 ± 3.34)

15 (8.49 ± 2.77)

0

S2 (378)

10 (8.67 ± 1.44)

220 (8.85 ± 3.20)

148 (10.54 ± 3.97)

0

S3 (325)

0

13 (9.89 ± 2.66)

268 (13.97 ± 6.87)

44 (17.24 ± 10.24)

S4 (183)

0

1 (9.5)

43 (14.78 ± 6.39)

139 (20.87 ± 11.84)

  1. S0 stage of fibrosis: t = − 1.002, P = 0.321
  2. S1 stage of fibrosis: F = 0.211, P = 0.81
  3. S2 stage of fibrosis: F = 10.664, P < 0.001; G1 versus G3, P = 0.01; G3 versus G2, P < 0.001
  4. S3 stage of fibrosis: F = 6.194, P = 0.002; G2 versus G3, P = 0.051; G2 versus G4, P = 0.002; G3 versus G4, P = 0.006
  5. S4 stage of fibrosis: G3 versus G4, t = − 4.358, P < 0.001