Controls (n = 47) | NAFLD (n = 125) | Mild (n = 79) | Moderate (n = 20) | Severe (n = 26) | |
---|---|---|---|---|---|
Gender (M/F) | 16/31 | 83/42 | 51/28 | 12/8 | 20/6 |
Age (years) | 42.81 ± 12.49 | 42.73 ± 13.03 | 44.51 ± 13.43 | 41.50 ± 11.39 | 37.50 ± 11.73 |
BMI (kg/m2) | 24.67 ± 3.99 | 27.98 ± 3.88a | 27.03 ± 3.44b | 28.52 ± 3.76c | 30.64 ± 4.11d |
TB (μmol/L) | 13.42 ± 4.31 | 15.65 ± 7.84 | 15.06 ± 8.82 | 16.51 ± 5.96c | 16.81 ± 5.55d |
ALT (U/L) | 30.33 ± 32.35 | 55.84 ± 42.85 a | 43.86 ± 37.93b | 58.77 ± 35.19c | 90.88 ± 44.53d |
AST (U/L) | 26.43 ± 17.44 | 34.81 ± 20.80 | 31.03 ± 22.24 | 35.37 ± 14.87c | 46.16 ± 16.01d |
ALP (U/L) | 77.04 ± 28.73 | 87.88 ± 26.49 | 91.27 ± 24.34b | 81.30 ± 20.82 | 83.39 ± 34.71 |
GGT (U/L) | 38.52 ± 56.12 | 54.52 ± 52.17 | 52.01 ± 53.39 | 51.28 ± 44.51 | 64.44 ± 54.96 |
FPG (mmol/L) | 5.05 ± 1.35 | 5.73 ± 1.95 | 5.87 ± 2.31 | 5.64 ± 1.06 | 5.38 ± 0.98 |
UA (μmol/L) | 362.10 ± 115.67 | 427.20 ± 122.89a | 406.06 ± 115.54b | 410.21 ± 105.99 | 503.37 ± 130.70d |
TC (mmol/L) | 1.52 ± 1.38 | 2.77 ± 2.55a | 2.48 ± 2.79b | 3.34 ± 2.05c | 3.18 ± 2.02d |
TG (mmol/L) | 4.72 ± 1.42 | 4.93 ± 1.59 | 5.06 ± 1.61 | 4.51 ± 1.67 | 4.89 ± 1.46 |
LDL (mmol/L) | 2.63 ± 0.88 | 2.96 ± 0.92 a | 2.93 ± 0.83 | 2.98 ± 2.63 | 3.07 ± 1.33 |
HDL (mmol/L) | 1.50 ± 0.52 | 1.29 ± 0.56a | 1.32 ± 0.65 | 1.26 ± 0.40 | 1.23 ± 0.36d |
APOA1 (g/L) | 1.45 ± 0.54 | 1.57 ± 2.56 | 1.72 ± 3.20 | 1.37 ± 0.34 | 1.28 ± 0.54 |
APOB (g/L) | 1.02 ± 0.32 | 1.15 ± 0.30 | 1.15 ± 0.34b | 1.19 ± 0.25c | 1.13 ± 0.22 |
Insulin (%) | 7.98 ± 4.05 | 14.96 ± 15.11a | 14.46 ± 18.22b | 13.94 ± 5.66c | 17.46 ± 5.98d |
HbA1c (μmol/L) | 5.61 ± 0.90 | 5.99 ± 1.38 | 6.02 ± 1.57 | 5.94 ± 0.65 | 5.92 ± 1.15 |
UGT1A1 (ng/mL) | 1.63 ± 1.59 | 1.72 ± 1.56 | 1.64 ± 1.38 | 1.96 ± 1.82 | 1.74 ± 1.91 |
MRI-PDFF (%) | 3.92 ± 1.15 | 16.30 ± 7.93a | 11.25 ± 3.33b | 19.09 ± 2.42c | 27.86 ± 5.68d |