Skip to main content

Table 1 Characteristics of the Subjects that stratified according to MRI-PDFF value

From: Relationship of circulating total bilirubin, UDP-glucuronosyltransferases 1A1 and the development of non-alcoholic fatty liver disease: a cross-sectional study

 

Controls

(n = 47)

NAFLD

(n = 125)

Mild

(n = 79)

Moderate

(n = 20)

Severe

(n = 26)

Gender (M/F)

16/31

83/42

51/28

12/8

20/6

Age (years)

42.81 ± 12.49

42.73 ± 13.03

44.51 ± 13.43

41.50 ± 11.39

37.50 ± 11.73

BMI (kg/m2)

24.67 ± 3.99

27.98 ± 3.88a

27.03 ± 3.44b

28.52 ± 3.76c

30.64 ± 4.11d

TB (μmol/L)

13.42 ± 4.31

15.65 ± 7.84

15.06 ± 8.82

16.51 ± 5.96c

16.81 ± 5.55d

ALT (U/L)

30.33 ± 32.35

55.84 ± 42.85 a

43.86 ± 37.93b

58.77 ± 35.19c

90.88 ± 44.53d

AST (U/L)

26.43 ± 17.44

34.81 ± 20.80

31.03 ± 22.24

35.37 ± 14.87c

46.16 ± 16.01d

ALP (U/L)

77.04 ± 28.73

87.88 ± 26.49

91.27 ± 24.34b

81.30 ± 20.82

83.39 ± 34.71

GGT (U/L)

38.52 ± 56.12

54.52 ± 52.17

52.01 ± 53.39

51.28 ± 44.51

64.44 ± 54.96

FPG (mmol/L)

5.05 ± 1.35

5.73 ± 1.95

5.87 ± 2.31

5.64 ± 1.06

5.38 ± 0.98

UA (μmol/L)

362.10 ± 115.67

427.20 ± 122.89a

406.06 ± 115.54b

410.21 ± 105.99

503.37 ± 130.70d

TC (mmol/L)

1.52 ± 1.38

2.77 ± 2.55a

2.48 ± 2.79b

3.34 ± 2.05c

3.18 ± 2.02d

TG (mmol/L)

4.72 ± 1.42

4.93 ± 1.59

5.06 ± 1.61

4.51 ± 1.67

4.89 ± 1.46

LDL (mmol/L)

2.63 ± 0.88

2.96 ± 0.92 a

2.93 ± 0.83

2.98 ± 2.63

3.07 ± 1.33

HDL (mmol/L)

1.50 ± 0.52

1.29 ± 0.56a

1.32 ± 0.65

1.26 ± 0.40

1.23 ± 0.36d

APOA1 (g/L)

1.45 ± 0.54

1.57 ± 2.56

1.72 ± 3.20

1.37 ± 0.34

1.28 ± 0.54

APOB (g/L)

1.02 ± 0.32

1.15 ± 0.30

1.15 ± 0.34b

1.19 ± 0.25c

1.13 ± 0.22

Insulin (%)

7.98 ± 4.05

14.96 ± 15.11a

14.46 ± 18.22b

13.94 ± 5.66c

17.46 ± 5.98d

HbA1c (μmol/L)

5.61 ± 0.90

5.99 ± 1.38

6.02 ± 1.57

5.94 ± 0.65

5.92 ± 1.15

UGT1A1 (ng/mL)

1.63 ± 1.59

1.72 ± 1.56

1.64 ± 1.38

1.96 ± 1.82

1.74 ± 1.91

MRI-PDFF (%)

3.92 ± 1.15

16.30 ± 7.93a

11.25 ± 3.33b

19.09 ± 2.42c

27.86 ± 5.68d

  1. BMI, body mass index; TB, total bilirubin; ALT, alanine aminotransferase; AST, aspartate aminotransferase; ALP, alkaline phosphatase; GGT, γ-glutamyltransferase; FPG, fasting plasma glucose; UA, uric acid; TC, total cholesterol; TG, triglyceride; LDL, low-density lipoprotein; HDL, high-density lipoprotein; APOA1, apolipoprotein A1; APOB, apol ipoprotein B; HbA1c, Glycated hemoglobin; UGT1A1, UDP-glucuronosyltransferase 1A1
  2. aNAFLD versus controls, P < 0.05
  3. bMild steatosis versus controls, P < 0.05
  4. cModerate steatosis versus controls P < 0.05
  5. dSevere steatosis versus controls, P < 0.05