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Table 2 Comparison of outcomes between early infliximab induction and delayed infliximab induction groups

From: Combined therapy with early initiation of infliximab following drainage of perianal fistulising Crohn’s disease: a retrospective cohort study

Characteristics

Early infliximab induction (n = 73)

Delayed infliximab induction (n = 44)

p value

Duration of follow-up, months (IQR)

32.0 (21.0–60.5)

37.5 (33.5–57.25)

0.021

Initial surgery, n (%)

  

0.001

 Seton drainage

70 (95.9)

33 (75.0)

0.001

 Fistulotomy

2 (2.7)

8 (18.2)

0.011

 RAF

0 (0)

2 (4.5)

0.296

 LIFT

1 (1.4)

1 (2.3)

1.000

Medical treatment at last follow-up, n (%)

  

0.761

 Infliximab

10 (13.7)

3 (6.8)

0.524

 Immunomodulators

33 (45.2)

21 (47.7)

0.979

 5-ASA

4 (5.5)

3 (6.8)

0.934

 None

26 (35.6)

17 (38.6)

0.743

Re-intervention, n (%)

25 (34.2)

11 (25.0)

0.294

Fistula healing, n (%)

45 (61.6)

29 (65.9)

0.643

Re-intervention-free healing rate, n (%)

33 (45.2)

24 (54.6)

0.328

  1. IQR interquartile range, RAF rectal advancement flap, LIFT ligation of the intersphincteric fistula tract, 5-ASA 5-aminosalicylic acid