Table 2 Comparison of undifferentiated embryonal sarcoma of the liver, hepatoblastoma, mesenchymal hamartoma and embryonal rhabdomyosarcoma

UESL

Solid (USG), cystic mass with internal septations and serpiginous vessels (CT), hypointense (T1-weighted MRI), hyperintense (T2 MRI)

Abdominal pain, palpable mass, fever

Spindle and stellate pleomorphic cells in a myxoid stroma

Vimentin, α1-antitrypsin, CD10, CD56, CD68, BCL2

Solitary mass in the right lobe of the liver

Hepatoblastoma

Sometimes with lesion and hemorrhage in the mass (USG), attenuation values

Between water and normal liver parenchyma (CT), bands with low signal intensity compared with liver (T1-weighted MRI), bands with high signal intensity compared with liver (T2-weighted MRI)

Abdominal distension, abdominal mass

Various histological subtypes in different stages of liver development

CK19, beta-catenin, epcam

Mostly, a solitary mass in the right lobe of the liver

Mesenchymal hamartoma

Cystic mass with internal septations (USG), cystic mass with septal and solid stromal enhancement (CT/MRI), variable intensity (T1-weighted MRI), high signal intensity (T2-weighted MRI)

Abdominal distension, abdominal mass

Lobular growth of myxomatous connective tissue with branching bile ducts

Vimentin, α1-antitrypsin, actin, cytokeratin, desmin

Usually, a large solitary mass in the right lobe of the liver

Embryonal rhabdomyosarcoma

Dilation of the intra- and extrahepatic bile ducts with an intraductal mass (USG), signal of skeletal muscle (T1-weighted MRI), hyperintense (T2-weighted MRI)

Jaundice, abdominal pain, fever, vomiting

A condensed layer of neoplastic subepithelial cellularity (cambium layer)

Desmin, myogenin, Myo-D1

Biliary tract