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Table 1 Characteristics of the participants with and without NAFLD (N = 3239)

From: Comparison of several blood lipid-related indexes in the screening of non-alcoholic fatty liver disease in women: a cross-sectional study in the Pearl River Delta region of southern China

Variables Total Non-NAFLD (n = 2527) NAFLD* (n = 712) P
Age (years) 57.65 ± 12.53 57.23 ± 12.90 59.11 ± 11.04 < 0.001
Medical history     
Hypertension, n (%)     0.138
 Yes 1640 (50.6%) 1262 (77.0%) 378 (23.0%)  
 No 1599 (49.4%) 1265 (79.1%) 334 (20.9%)  
Diabetes, n (%)     0.012
 Yes 394 (12.2%) 288 (73.1%) 106 (26.9%)  
 No 2845 (87.8%) 2239 (78.7%) 606 (21.3%)  
Anthropometric indexes     
SBP (mmHg) 130.08 ± 18.58 128.93 ± 18.56 134.16 ± 18.07 < 0.001
DBP (mmHg) 81.15 ± 10.89 80.44 ± 10.85 83.66 ± 10.69 < 0.001
BMI (kg/m2) 24.40 ± 3.64 23.61 ± 3.29 27.20 ± 3.42 < 0.001
Routine blood test     
RBC (× 1012/L) 4.15 ± 1.06 4.13 ± 1.18 4.24 ± 0.42 0.020
WBC (× 109/L) 6.29 ± 1.58 6.12 ± 1.52 6.89 ± 1.67 < 0.001
Hb (g/L) 122.73 ± 11.09 121.73 ± 11.01 126.26 ± 10.68 < 0.001
PLT (× 109/L) 222.53 ± 55.20 219.71 ± 53.77 232.53 ± 58.99 < 0.001
Glucose level     
FPG (mmol/L) 4.73 (4.30–5.31) 4.68 (4.27–5.19) 4.97 (4.49–5.87) < 0.001
HbAlc (%) 5.30 (5.00–5.60) 5.30 (5.00–5.60) 5.40 (5.10–5.90) < 0.001
Liver function test     
ALT (U/L) 21.00 (16.00–27.00) 19.00 (16.00–24.00) 27.00 (21.00–36.00) < 0.001
AST (U/L) 22.00 (19.00–26.00) 22.00 (19.00–25.00) 24.00 (21.00–29.75) < 0.001
ALP (U/L) 80.88 ± 23.45 79.79 ± 24.01 84.75 ± 20.91 < 0.001
GGT (U/L) 24.00 (19.00–33.00) 23.00 (19.00–30.00) 33.00 (25.00–45.00) < 0.001
TBIL (μmol/L) 12.17 ± 5.22 12.32 ± 5.53 11.65 ± 3.89 0.003
Renal function test     
Scr (μmol/L) 78.40 (74.90–80.00) 78.20 (74.70–80.00) 78.90 (75.50–80.98) < 0.001
BUN (mmol/L) 4.90 (4.00–5.90) 4.90 (4.00–5.90) 5.00 (4.10–6.00) 0.047
UA (μmol/L) 328.79 ± 98.16 317.88 ± 97.42 367.54 ± 90.74 < 0.001
Blood lipid test     
TC (mmol/L) 5.20 ± 1.42 5.14 ± 1.05 5.41 ± 2.28 0.002
TG (mmol/L) 1.34 (0.96–1.92) 1.22 (0.90–1.71) 1.84 (1.35–2.59) < 0.001
HDL-C (mmol/L) 1.35 ± 0.33 1.38 ± 0.34 1.24 ± 0.28 < 0.001
LDL-C (mmol/L) 2.85 ± 1.04 2.81 ± 0.95 3.01 ± 1.30 < 0.001
Blood lipid-related indexes     
CMI 0.78 ± 0.91 0.67 ± 0.82 1.17 ± 1.08 < 0.001
TyG 8.61 ± 0.63 8.50 ± 0.58 8.99 ± 0.65 < 0.001
TG/HDL-C 1.43 ± 1.71 1.26 ± 1.61 2.02 ± 1.92 < 0.001
TC/HDL-C 4.05 ± 1.44 3.90 ± 1.22 4.55 ± 1.97 < 0.001
LDL-C/HDL-C 2.23 ± 0.97 2.14 ± 0.85 2.54 ± 1.28 < 0.001
  1. Data are presented as the n (%), mean ± standard deviation (SD) or median (interquartile range)
  2. NAFLD non-alcoholic fatty liver disease, SBP systolic blood pressure, DBP diastolic blood pressure, BMI body mass index, RBC red blood cell, WBC white blood cell, Hb hemoglobin, PLT platelet, FPG fasting plasma glucose, HbAlc glycated hemoglobin, ALT alanine aminotransferase, AST aspartate aminotransferase, ALP alkaline phosphatase, GGT γ-glutamyl transpeptidase, TBIL total bilirubin, Scr serum creatinine, BUN blood urea nitrogen, UA uric acid, TC total cholesterol, TG triglyceride, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, CMI cardiometabolic index, TyG triglyceride glucose
  3. *Mild NAFLD: 316 (44.4%); moderate NAFLD: 110 (15.4%); severe NAFLD: 15 (2.1%); unreported severity: 271 (38.1%)