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Table 1 Characteristics of the participants with and without NAFLD (N = 3239)

From: Comparison of several blood lipid-related indexes in the screening of non-alcoholic fatty liver disease in women: a cross-sectional study in the Pearl River Delta region of southern China

Variables

Total

Non-NAFLD (n = 2527)

NAFLD* (n = 712)

P

Age (years)

57.65 ± 12.53

57.23 ± 12.90

59.11 ± 11.04

< 0.001

Medical history

    

Hypertension, n (%)

   

0.138

 Yes

1640 (50.6%)

1262 (77.0%)

378 (23.0%)

 

 No

1599 (49.4%)

1265 (79.1%)

334 (20.9%)

 

Diabetes, n (%)

   

0.012

 Yes

394 (12.2%)

288 (73.1%)

106 (26.9%)

 

 No

2845 (87.8%)

2239 (78.7%)

606 (21.3%)

 

Anthropometric indexes

    

SBP (mmHg)

130.08 ± 18.58

128.93 ± 18.56

134.16 ± 18.07

< 0.001

DBP (mmHg)

81.15 ± 10.89

80.44 ± 10.85

83.66 ± 10.69

< 0.001

BMI (kg/m2)

24.40 ± 3.64

23.61 ± 3.29

27.20 ± 3.42

< 0.001

Routine blood test

    

RBC (× 1012/L)

4.15 ± 1.06

4.13 ± 1.18

4.24 ± 0.42

0.020

WBC (× 109/L)

6.29 ± 1.58

6.12 ± 1.52

6.89 ± 1.67

< 0.001

Hb (g/L)

122.73 ± 11.09

121.73 ± 11.01

126.26 ± 10.68

< 0.001

PLT (× 109/L)

222.53 ± 55.20

219.71 ± 53.77

232.53 ± 58.99

< 0.001

Glucose level

    

FPG (mmol/L)

4.73 (4.30–5.31)

4.68 (4.27–5.19)

4.97 (4.49–5.87)

< 0.001

HbAlc (%)

5.30 (5.00–5.60)

5.30 (5.00–5.60)

5.40 (5.10–5.90)

< 0.001

Liver function test

    

ALT (U/L)

21.00 (16.00–27.00)

19.00 (16.00–24.00)

27.00 (21.00–36.00)

< 0.001

AST (U/L)

22.00 (19.00–26.00)

22.00 (19.00–25.00)

24.00 (21.00–29.75)

< 0.001

ALP (U/L)

80.88 ± 23.45

79.79 ± 24.01

84.75 ± 20.91

< 0.001

GGT (U/L)

24.00 (19.00–33.00)

23.00 (19.00–30.00)

33.00 (25.00–45.00)

< 0.001

TBIL (μmol/L)

12.17 ± 5.22

12.32 ± 5.53

11.65 ± 3.89

0.003

Renal function test

    

Scr (μmol/L)

78.40 (74.90–80.00)

78.20 (74.70–80.00)

78.90 (75.50–80.98)

< 0.001

BUN (mmol/L)

4.90 (4.00–5.90)

4.90 (4.00–5.90)

5.00 (4.10–6.00)

0.047

UA (μmol/L)

328.79 ± 98.16

317.88 ± 97.42

367.54 ± 90.74

< 0.001

Blood lipid test

    

TC (mmol/L)

5.20 ± 1.42

5.14 ± 1.05

5.41 ± 2.28

0.002

TG (mmol/L)

1.34 (0.96–1.92)

1.22 (0.90–1.71)

1.84 (1.35–2.59)

< 0.001

HDL-C (mmol/L)

1.35 ± 0.33

1.38 ± 0.34

1.24 ± 0.28

< 0.001

LDL-C (mmol/L)

2.85 ± 1.04

2.81 ± 0.95

3.01 ± 1.30

< 0.001

Blood lipid-related indexes

    

CMI

0.78 ± 0.91

0.67 ± 0.82

1.17 ± 1.08

< 0.001

TyG

8.61 ± 0.63

8.50 ± 0.58

8.99 ± 0.65

< 0.001

TG/HDL-C

1.43 ± 1.71

1.26 ± 1.61

2.02 ± 1.92

< 0.001

TC/HDL-C

4.05 ± 1.44

3.90 ± 1.22

4.55 ± 1.97

< 0.001

LDL-C/HDL-C

2.23 ± 0.97

2.14 ± 0.85

2.54 ± 1.28

< 0.001

  1. Data are presented as the n (%), mean ± standard deviation (SD) or median (interquartile range)
  2. NAFLD non-alcoholic fatty liver disease, SBP systolic blood pressure, DBP diastolic blood pressure, BMI body mass index, RBC red blood cell, WBC white blood cell, Hb hemoglobin, PLT platelet, FPG fasting plasma glucose, HbAlc glycated hemoglobin, ALT alanine aminotransferase, AST aspartate aminotransferase, ALP alkaline phosphatase, GGT γ-glutamyl transpeptidase, TBIL total bilirubin, Scr serum creatinine, BUN blood urea nitrogen, UA uric acid, TC total cholesterol, TG triglyceride, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, CMI cardiometabolic index, TyG triglyceride glucose
  3. *Mild NAFLD: 316 (44.4%); moderate NAFLD: 110 (15.4%); severe NAFLD: 15 (2.1%); unreported severity: 271 (38.1%)
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BMC Gastroenterology

ISSN: 1471-230X

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