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Table 2 Summary of 19 cases in which chemotherapy was used for treatment

From: Unresectable primary hepatic adenosquamous carcinoma successfully treated with systemic and transcatheter hepatic arterial injection chemotherapies followed by conversion surgery: a case report and literature review

No. Regimen Object Administration route Response Prognosis References
1 5-FU + CDDP Adj Intravenously NR Alive, 8 months after surgery [27]
2 GEM + S-1 Adj Intravenously NR Alive, 8 months after surgery [37]
3 5-FU Adj Intravenously NR Alive, 15 months after surgery [21]
4 Capecitabine Adj Oral NR Alive, 15 months after surgery [46]
5 Sorafenib Adj Oral NR Alive, 7 months after surgery [46]
6 Capecitabine Adj Oral R Dead [46]
7 contents unknown Adj n.a R Dead, 8 months after surgery [19]
8 contents unknown Chemo n.a PD Dead [20]
9 contents unknown Chemo n.a PD Dead [46]
10 contents unknown Chemo n.a PD Dead [46]
11 contents unknown Chemo n.a PD Dead [46]
12 5-FU + CDDP Chemo TAI PD Dead, 14 months after diagnosis [45]
13 5-FU + CDDP Chemo TAI PD Dead, 13 months after diagnosis [36]
14 GEM + CDDP Chemo Intravenously PD Dead [39]
15 GEM + S-1 Chemo Intravenously PD Dead, 10 months after surgery [17]
16 5-FU + CDDP Chemo TAI PR Alive, 8 months after chemo [28]
17 5-FU + CDDP Chemo TAI PR Alive, 8 months after chemo [29]
18 GEM + CDDP Chemo Intravenously PR Alive, 11 months after surgery [41]
19 S-1 + CDDP Conversion therapy TAI PR Alive, 6 months after surgery Our case
  1. Adj, Adjuvant chemotherapy; Cx, Chemotherapy; CDDP, cisplatin; GEM, gemcitabine; n.a., not applicable; No., number; NR, no recurrence; PD, progressive disease; PR, partial remission; R, recurrence; Ref, Reference; S-1, Tegafur/Gimeracil/Oteracil; TAI, transcatheter hepatic arterial injection; 5-FU, 5-fluorouracil