Table 4 Association between the ABCG8 rs11887534 variant and gallstones in the female study participants

ABCG8 rs11887534 genotype

 GG (reference)

–

–

–

–

 GC + CC

1.789

1.208

2.648

0.0037

Hormone use

 No (reference)

–

–

–

–

 Yes

1.359

1.107

1.668

0.0033

Menopause

 No (reference)

–

–

–

–

 Yes

1.250

0.934

1.672

0.1332

Age

1.042

1.027

1.058

< .0001

Regular exercise

 No (reference)

–

–

–

–

 Yes

0.816

0.682

0.976

0.0260

Cigarette smoking

 No (reference)

–

–

–

–

 Yes

1.243

0.827

1.869

0.2963

Alcohol drinking

 No (reference)

–

–

–

–

 Yes

1.317

0.786

2.205

0.2955

BMI

 Normal (reference)

–

–

–

–

 Underweight

0.900

0.518

1.565

0.7099

 Overweight

1.307

1.069

1.598

0.0090

 Obesity

1.189

0.931

1.520

0.1660

Family history of gallstones

 No (reference)

–

–

–

–

 Yes

1.730

1.332

2.246

< .0001

Diabetes

 No (reference)

–

–

–

–

 Yes

1.054

0.805

1.380

0.6998

Total bilirubin

1.875

1.348

2.606

0.0002

AST

0.986

0.972

1.001

0.0709

ALT

1.011

1.002

1.021

0.0215

HDL-C (mg/dL)

0.988

0.981

0.996

0.0020

LDL-C (mg/dL)

0.997

0.994

0.999

0.0125

TG (mg/dL)

1.000

0.999

1.001

0.7819

Dietary fat score

1.005

0.995

1.014

0.3421