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Table 4 Association between the ABCG8 rs11887534 variant and gallstones in the female study participants

From: Risk of gallstones based on ABCG8 rs11887534 single nucleotide polymorphism among Taiwanese men and women

Variables OR 95% CI P-value
ABCG8 rs11887534 genotype     
 GG (reference)
 GC + CC 1.789 1.208 2.648 0.0037
Hormone use     
 No (reference)
 Yes 1.359 1.107 1.668 0.0033
Menopause     
 No (reference)
 Yes 1.250 0.934 1.672 0.1332
Age 1.042 1.027 1.058 < .0001
Regular exercise     
 No (reference)
 Yes 0.816 0.682 0.976 0.0260
Cigarette smoking     
 No (reference)
 Yes 1.243 0.827 1.869 0.2963
Alcohol drinking     
 No (reference)
 Yes 1.317 0.786 2.205 0.2955
BMI     
 Normal (reference)
 Underweight 0.900 0.518 1.565 0.7099
 Overweight 1.307 1.069 1.598 0.0090
 Obesity 1.189 0.931 1.520 0.1660
Family history of gallstones     
 No (reference)
 Yes 1.730 1.332 2.246 < .0001
Diabetes     
 No (reference)
 Yes 1.054 0.805 1.380 0.6998
Total bilirubin 1.875 1.348 2.606 0.0002
AST 0.986 0.972 1.001 0.0709
ALT 1.011 1.002 1.021 0.0215
HDL-C (mg/dL) 0.988 0.981 0.996 0.0020
LDL-C (mg/dL) 0.997 0.994 0.999 0.0125
TG (mg/dL) 1.000 0.999 1.001 0.7819
Dietary fat score 1.005 0.995 1.014 0.3421
  1. OR odds ratio, CI confidence interval, ABCG8 ATP-binding cassette subfamily G Member 8, BMI body mass index, AST aspartate aminotransferase, ALT alanine transaminase, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, TG triglyceride