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Table 3 Epidemiology and laboratory parameters of Crohn’ s disease patients, stratified by disease activity

From: Predictive value of fibrinogen in identifying inflammatory bowel disease in active stage

Parameter

CD remission (N = 257)

CD active (N = 286)

P value

Age (years)

27 (22–30)

26 (22–36)

0.641

Sex: male

185 (72.0)

211 (73.8)

0.639

BMI (kg/m2)

19.6 (18.3–21.6)

18.2 (16.4–20.2)

 < 0.001

Smoking: yes

35 (13.6)

49 (17.1)

0.258

Drinking: yes

14 (5.4)

30 (10.5)

0.032

Duration of disease (years)

2.0 (1.0–3.5)

1.1 (0.3–3.5)

 < 0.001

Neutrophil (109/L)

3.5 (2.7–4.4)

5.1 (3.5–7.1)

 < 0.001

Monocyte (109/L)

0.5 (0.4–0.6)

0.7 (0.5–0.9)

 < 0.001

Lymphocyte (109/L)

1.5 (1.1–1.9)

1.2 (0.9–1.7)

 < 0.001

Hb (g/dL)

13.5 (12.2–14.7)

11.5 (10.1–12.6)

 < 0.001

RDW (%)

13.4 (12.7–14.9)

14.8 (13.3–16.6)

 < 0.001

Platelet (109/L)

246 (206–294)

328 (254–414)

 < 0.001

PT (seconds)

13.5 (13.1–14.0)

14.0 (13.3–14.7)

 < 0.001

INR

1.1 (1.0–1.1)

1.1 (1.0–1.2)

 < 0.001

Fibrinogen (g/L)

3.0 (2.4–3.6)

4.7 (3.9–5.6)

 < 0.001

CRP (mg/L)

3.0 (1.6–8.6)

30.0 (15.6–60.4)

 < 0.001

ESR (mm/h)

7 (2–14)

31 (17–48)

 < 0.001

NLR

2.2 (1.6–3.3)

4.1 (2.8–6.2)

 < 0.001

PLR

168.3 (118.8–231.9)

264.8 (192.1–370.0)

 < 0.001

LMR

3.0 (2.3–4.2)

1.9 (1.4–2.6)

 < 0.001

  1. Values are expressed as n (%) or median (IQR). CD, Crohn’ s disease; BMI body mass index; Hb hemoglobin; RDW red cell distribution width; PT prothrombin time; INR international normalized ratio; CRP C-reactive protein; ESR erythrocyte sedimentation rate; NLR neutrophil to lymphocyte ratio; PLR platelet to lymphocyte ratio; LMR lymphocyte to monocyte ratio