The effects of preoperative intestinal dysbacteriosis on postoperative recovery in colorectal cancer surgery: a prospective cohort study

Table 5 Logistic regression of postoperative diarrhoea

Exposure	Univariate logistic regression		Multivariate logistic regression^‡
Exposure	OR (95%CI)	P	Adjusted OR (95%CI)	P
Preoperative dysbacteriosis^†
Grade 2	4.59 (2.46–8.55)	< 0.001	4.53 (2.28–9.00)	< 0.001
Grade 3	5.62 (2.45–12.88)	< 0.001	4.52 (1.81–11.31)	0.001
Surgical approach (laparoscopic)	1.94 (0.99–3.81)	0.052	2.30 (1.07–4.93)	0.033
BMI (≥ 25.0 kg/m²)	1.85 (1.06–3.24)	0.031	2.62 (1.37–5.00)	0.004
Intraoperative blood loss (≥ 100 ml)	2.00 (1.13–3.53)	0.017	1.69 (0.87–3.28)	0.122
Length of antibiotics therapy > 3 days	4.33 (2.42–7.75)	< 0.001	4.30 (2.21–8.39)	< 0.001

^†Reference group: Grade 1
^‡Hosmer–Lemeshow test x²= 3.574, P = 0.734
Abbreviations: BMI body mass index, OR odds ratio, 95 CI 95 confidence interval

ISSN: 1471-230X