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Table 2 Etiology of chronic diarrhea in this cohort

From: Diagnostic yield of esophagogastroduodenoscopy, colonoscopy, and small bowel endoscopy in Thai adults with chronic diarrhea

Diseases Number of patients (%)
(N = 550)
Infections
 Parasites/Protozoa 27 (4.91%)
 Tuberculosis 19 (3.45%)
 Cytomegalovirus 19 (3.45%)
 Clostridium difficile infection* 8 (1.45%)
 Bacteria other than C. difficile 5 (0.91%)
Neoplasm
 Colonic adenocarcinoma 40 (7.27%)
 Gastrointestinal lymphoma 9 (1.64%)
 Polyposis syndrome (Peutz-Jeghers syndrome, Cronkhite-Canada syndrome) 2 (0.36%)
Inflammatory bowel disease
 Crohn’s disease 20 (3.64%)
 Ulcerative colitis 31 (5.64%)
Microscopic colitis 5 (0.91%)
Systemic autoimmune diseases
 Systemic lupus erythematosus 5 (0.91%)
 Behcet’s disease 3 (0.55%)
Drugs
 Nonsteroidal anti-inflammatory agents 14 (2.55%)
 Chemotherapy/targeted therapy 9 (1.64%)
 Others e.g. colchicine, metformin 7 (1.27%)
Eosinophilic gastroenteritis 24 (4.36%)
Radiation enterocolitis 7 (1.27%)
Ischemic enterocolitis 3 (0.55%)
Graft-versus-host diseases 4 (0.73%)
Gastrointestinal amyloidosis 3 (0.55%)
Small intestinal bacterial overgrowth 21 (3.82%)
Pancreatic diseases
 Chronic pancreatitis 6 (1.09%)
 Pancreatic cancer 4 (0.73%)
 Status post pancreatic resection 1 (0.18%)
Endocrinologic diseases
 Diabetic diarrhea 16 (2.91%)
 Hyperthyroidism 3 (0.55%)
 Adrenal insufficiency 2 (0.36%)
Bile salt diarrhea 4 (0.73%)
Lactose intolerance 2 (0.36%)
Irritable bowel syndrome 215 (39.09%)
Idiopathic ulcers of intestine 4 (0.73%)
Idiopathic diarrhea 2 (0.36%)
Others (1 per each etiology): tropical sprue, intestinal lymphangiectasia, systemic mastocytosis, mesenteric neuroendocrine tumor, chronic diverticulitis, portal hypertensive colopathy) 6 (1.09%)
  1. EGD esophagogastroduodenoscopy, SD standard deviation, IQR interquartile range
  2. *Presumed Clostridium difficile infection was defined as endoscopic findings of pseudomembranous colitis with response to metronidazole or oral vancomycin