Skip to main content

Table 3 Univariable and multivariable Cox‐proportional hazard model for disease-free survival in BCLC very-early stage hepatocellular carcinoma patients

From: Clinical outcomes of surgical resection versus radiofrequency ablation in very-early‐stage hepatocellular carcinoma: a propensity score matching analysis

Characteristics Univariate Cox regression analyses Multivariate Cox regression analyses
Unadjusted HR (95% CI) P-value Adjusted HR (95% CI) P-value
Treatment type (SR vs. RFA) 1.35 (0.86–2.11) 0.193   
Male 0.97 (0.60–1.56) 0.903   
Age (≥ 60y vs, < 60y) 0.49 (0.31–0.76) 0.002 0.47 (0.30–0.73) 0.001
BMI (≥ 24 kg/m2 vs. < 24 kg/m2) 1.29 (0.83–2.02) 0.256   
Alcohol use 1.04 (0.63–1.72) 0.871   
HBV 1.29 (0.83–2.03) 0.256   
HCV 0.73 (0.47–1.14) 0.164   
Child‐Pugh class A 1.14 (0.42–3.13) 0.795   
Cirrhosis 0.59 (0.37–0.96) 0.032 0.56 (0.35–0.90) 0.018
Ascites 0.76 (0.35–1.65) 0.482   
Total bilirubin (≥ 1.3 mg/dL vs. < 1.3 mg/dL) 0.87 (0.52–1.47) 0.609   
Albumin (≥ 3.5 g/dL vs. < 3.5 g/dL) 1.08 (0.50–2.36) 0.840   
ALBI grade 1 vs. 2/3 0.82 (0.39–1.70) 0.589   
AFP (≥ 200 ng/ml vs. < 200 ng/ml) 0.78 (0.44–1.40) 0.406   
Tumor size (≥ 1.8 cm vs. < 1.8 cm) 1.19 (0.75–1.87) 0.467   
  1. CI: Conference Incidence; SR: Surgical resection; BMI: Body mass index; HBV: Hepatitis B virus; HCV: Hepatitis C virus; ALBI: Albumin- bilirubin; AFP: Alpha-fetoprotein