Fig. 6

MKI67 co-expression genes in LIHC (LinkedOmics). a MKI67-related genes in LIHC discovered by Pearson’s test. Green and red dots indicate genes with significant negative and positive correlations with MKI67, separately; b, c Heatmaps displaying 50 most significant MKI67-related genes in LIHC (both positive and negative); d, e Significantly associated GO: BP annotations together with KEGG pathway analysis for MKI67 in LIHC; f, g survival heatmaps displaying the 50 most significant MKI67-related genes in LIHC (both positive and negative). Survival heatmaps displaying the log10 HRs of diverse genes. Blue and red blocks represent decreased and increased risks distinctly. Rectangles with frames represent significantly positive and negative outcomes upon prognosis analysis (P < 0.05). GO Gene Ontology, KEGG Kyoto Encyclopedia of Genes and Genomes, FDR false discovery rate, LIHC Liver hepatocellular carcinoma; h MKI67 and its predicted miRNAs (MKI67 presented in yellow circles and targeted miRNAs presented in blue circles. The interaction between the MKI67 and related miRNAs is represented in the form of lines)