Table 1 Distribution of candidate predictors and outcomes in study cohort (N = 11,724)
| Variable | Distribution |
|---|---|
| Major Colonoscopy Indication: Signs/symptoms | 39.6% |
| Major Colonoscopy Indication: First-degree relative with CRC | 24.9% |
| Major Colonoscopy Indication: Surveillance (history of polyps) | 14.3% |
| Major Colonoscopy Indication: Asymptomatic screening* | 28.2% |
| Symptom Indication: Rectal bleeding | 19.7% |
| Symptom Indication: Anemia | 7.4% |
| Symptom Indication: Unintentional weight loss | 1.6% |
|
Symptom Indication: Other gastrointestinal symptoms (abdominal or rectal pain, new diarrhea or constipation, rectal urgency, fecal incontinence) | 20.3% |
| Age in years (median (IQR)) | 61 (55–68) |
| Male sex | 46% |
| Charlson-Deyo co-morbidity score | |
| 0–1 | 93.2% |
| 2 + | 6.8% |
| History of diabetes mellitus | 17.6% |
| Prior gastrointestinal malignancy (excluding CRC) | 0.5% |
| Any prior malignancy (excluding CRC) | 11.1% |
| Lower endoscopy within past 10 years | 42.3% |
| # Years since most recent lower endoscopy | |
| < 2 | 4.9% |
| 2–4 | 9.6% |
| 4–6 | 18.0% |
| 6–8 | 6.7% |
| 8–10 | 3.1% |
| > 10 (or none) | 57.7% |
| Complete colonoscopy (to cecum) within past 10 years | 37.9% |
| Polypectomy or polyp fulguration within past 10 years | 15.6% |
| Highest neoplasia grade at colonoscopy | |
| Invasive cancer | 1.5% |
| High-risk adenoma** | 11.5% |
| Low-risk adenoma or normal | 87% |