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Table 1 Distribution of candidate predictors and outcomes in study cohort (N = 11,724)

From: Multivariable models for advanced colorectal neoplasms in screen-eligible individuals at low-to-moderate risk of colorectal cancer: towards improving colonoscopy prioritization

Variable Distribution
Major Colonoscopy Indication: Signs/symptoms 39.6%
Major Colonoscopy Indication: First-degree relative with CRC 24.9%
Major Colonoscopy Indication: Surveillance (history of polyps) 14.3%
Major Colonoscopy Indication: Asymptomatic screening* 28.2%
Symptom Indication: Rectal bleeding 19.7%
Symptom Indication: Anemia 7.4%
Symptom Indication: Unintentional weight loss 1.6%
Symptom Indication: Other gastrointestinal symptoms
(abdominal or rectal pain, new diarrhea or constipation, rectal urgency, fecal incontinence)
20.3%
Age in years (median (IQR)) 61 (55–68)
Male sex 46%
Charlson-Deyo co-morbidity score  
 0–1 93.2%
 2 +  6.8%
History of diabetes mellitus 17.6%
Prior gastrointestinal malignancy (excluding CRC) 0.5%
Any prior malignancy (excluding CRC) 11.1%
Lower endoscopy within past 10 years 42.3%
# Years since most recent lower endoscopy  
 < 2 4.9%
 2–4 9.6%
 4–6 18.0%
 6–8 6.7%
 8–10 3.1%
 > 10 (or none) 57.7%
Complete colonoscopy (to cecum) within past 10 years 37.9%
Polypectomy or polyp fulguration within past 10 years 15.6%
Highest neoplasia grade at colonoscopy  
Invasive cancer 1.5%
 High-risk adenoma** 11.5%
 Low-risk adenoma or normal 87%
  1. *Default indication if the three other major colonoscopy indications (signs or symptoms, family history, surveillance) were negative
  2. **≥ 3 adenomas, adenoma ≥ 1 cm or adenoma with villous/serrated/high-grade dysplastic features