Table 2 Univariate and multivariate analysis of prognostics factors for recurrence in NBNC-HCC patients after curative resection
Variable | Comparison | Univariate | Multivariate | ||
|---|---|---|---|---|---|
HR (95%CI) | p value | HR (95%CI) | p value | ||
Age (years) | > 60 vs ≦ 60 | 1.316 (0.815–2.125) | 0.216 | ||
Sex | Male vs. Female | 1.220 (0.698–2.131) | 0.485 | ||
DM history | Yes vs. no | 1.286 (0.800–2.068) | 0.299 | ||
Hypertension | Yes vs. no | 1.184 (0.694–2.020) | 0.536 | ||
Alcoholic history | Yes vs. no | 1.353 (0.748–2.446) | 0.318 | ||
AFP (ng/ml) | > 200 vs. ≦ 200 | 2.065 (1.149–3.710) | 0.015 | 2.070 (1.114–3.848) | 0.021 |
Platelet (\({10}^{9}\)/L) | ≦ 150 vs. > 150 | 1.264 (0.754–2.119) | 0.375 | ||
Albumin (g/dL) | ≦ 3 vs. > 3 | 1.358 (0.833–2.215) | 0.220 | ||
Liver cirrhosis | Yes vs. no | 0.950 (0.552–1.635) | 0.853 | ||
Child–Pugh grade | B vs. A | 1.216 (0.682–2.168) | 0.508 | ||
ALBI grade | II/III vs. I | 1.052 (0.662–1.671) | 0.831 | ||
Tumor size (cm) | > 5 vs. ≦ 5 | 1.024 (0.634–1.653) | 0.923 | ||
Tumor no | Multiple vs. single | 2.847 (0.892–9.084) | 0.077 | 10.770 (2.513–46.153) | 0.001 |
BCLC stage | B vs. 0/A | 1.004 (0.625–1.615) | 0.985 | ||
Liver fat content (%) | > 30 vs. ≦ 30 | 1.472 (0.811–2.673) | 0.204 | ||
Microvascular invasion | Yes vs. no | 0.798 (0.479–1.329) | 0.386 | ||
pTNM stages | II + III vs. I | 2.084 (1.302–3.336) | 0.002 | 1.962 (1.199–3.210) | 0.007 |
Histology stages | Poor vs. well/moderate | 1.699 (0.682–4.232) | 0.255 | ||