Table 1 Genomic profiling results of each tumor sites
From: Genomic profiling of a patient with quadruple synchronous colorectal cancer: a case report
Tumor site | Pathology type | Tumor content (%) | Identified mutations and MSI status* | |
|---|---|---|---|---|
Tumor 1 | Ascending colon | Intraepithelial neoplasia (high-grade) | 70 | KRAS p.G13D(35.27%) APC p.R283*(32.94%) PIK3CA p.E545K(4.34%) MSS |
Tumor 2 | Rectum | Neuroendocrine tumor (G1) | 10 | APC p.S1315*(25.81%) MSS |
Tumor 3 | Sigmoid colon | Adenocarcinoma (moderate differentiation) | 60 | ERBB2 amp (CN: 3.0) APC p.S1400*(40.52%) APC p.R302*(17.90%) PIK3CA p.E542K(21.72%) TP53 p.A159V(58.79%) MSS |
Tumor 4 | Rectum | Adenocarcinoma (moderate differentiation) | 3 | APC p.R232*(2.32%) TP53 p.T125(2.90%) MSS |