Glucocorticoids in acute pancreatitis: a propensity score matching analysis

BMC Gastroenterology

Table 3 Fluid resuscitation-related characteristics

Characteristic	Original cohort (n = 818)		P	Matched cohort (n = 118)		P
Characteristic	GC group (n = 76)	NGC group (n = 742)	P	GC group (n = 59)	NGC group (n = 59)	P
Amount of resuscitation fluids within the first 8 h, mL	2814.8 ± 428.1	1533.4 ± 297.4	< 0.001*	2774.1 ± 413.8	2711.8 ± 391.4	0.947
Total fluid balance within
8 h, mL	2348.4 ± 401.9	1108.74 ± 259.3	< 0.001*	2270.1 ± 394.5	2318.8 ± 401.9	0.884
24 h, mL	1798.1 ± 394.8	1342.9 ± 377.4	0.022*	1763.1 ± 381.4	1790.9 ± 341.3	0.941
48 h, mL	1371.8 ± 331.4	896.7 ± 294.3	0.039*	1355.6 ± 324.7	2057.1 ± 313.1	0.012*
72 h, mL	1159.1 ± 284.2	730.1 ± 251.1	0.007*	1189.4 ± 267.4	2545.1 ± 338.7	< 0.001*
Hemodynamic and perfusion-related variables at 72 h
Heart rate, /min	113.1 ± 10.9	83.7 ± 11.3	< 0.001*	110.9 ± 10.7	119.4 ± 12.7	0.374
CVP, cm H₂0^#	11.8 ± 2.1	9.3 ± 1.9	0.127	11.7 ± 2.1	16.5 ± 2.3	< 0.001*
Serum lactate, mmol/L	2.3 ± 0.9	1.2 ± 0.5	0.133	2.3 ± 0.9	2.7 ± 1.1	0.243

*Significant difference
^#CVP, Central venous pressure. CVP was measured only in patients who had a central venous catheter. All the patients in the GC group (n = 76) had measured the CVP. In NGC group, not all patients measured CVP (n = 314, before matching; n = 57, after matching)

ISSN: 1471-230X