Table 2 Main Clinical Outcomes of the Study
From: Glucocorticoids in acute pancreatitis: a propensity score matching analysis
Characteristic | Original cohort (n = 818) | P | Matched cohort (n = 118) | P | ||
|---|---|---|---|---|---|---|
GC group (n = 76) | NGC group (n = 742) | GC group (n = 59) | NGC group (n = 59) | |||
Mortality, n (%) | 3 (3.9%) | 18 (2.4%) | 0.676 | 3 (5.1%) | 8 (13.6%) | 0.113 |
Severe acute pancreatitis, n (%) | 25 (32.9%) | 208 (28.0%) | 0.371 | 23 (39.0%) | 33 (55.9%) | 0.065 |
Organ failure | ||||||
 Patient number, n (%) | 24 (31.6%) | 185 (24.9%) | 0.206 | 20 (40.7%) | 31 (52.5%) | 0.041* |
 Duration, n (%) | ||||||
   < 48 h | 13 (54.2%) | 118 (63.8%) | 0.785 | 10 (50.0%) | 12 (38.7%) | 0.636 |
   ≥ 48 h | 11 (45.8%) | 67 (36.2%) | 0.124 | 10 (50.0%) | 19 (61.3%) | 0.054 |
 Organs involved, n (%) | ||||||
  Single | 16 (66.7%) | 163 (88.1%) | 0.854 | 13 (65.0%) | 10 (32.3%) | 0.486 |
  Mutiple | 8 (33.3%) | 22 (11.9%) | 0.003* | 7 (35.0%) | 21 (67.7%) | 0.002* |
Further interventions needed, n (%) | ||||||
 APD | 15 (19.7%) | 139 (18.7%) | 0.831 | 11 (18.6%) | 17 (28.8%) | 0.194 |
 PCD | 10 (13.2%) | 72 (9.7%) | 0.340 | 8 (13.6%) | 13 (22.0%) | 0.229 |
 Minimally invasive interventions | 5 (6.6%) | 24 (3.2%) | 0.240 | 4 (6.8%) | 7 (11.9%) | 0.342 |
 Open operation | 2 (2.6%) | 11 (1.5%) | 0.778 | 2 (3.4%) | 3 (5.1%) | 0.648 |
Antibiotic usage, n (%) | 39 (51.3%) | 348 (46.9%) | 0.463 | 28 (47.5%) | 29 (49.2%) | 0.854 |
Glucocorticoids related adverse events | ||||||
 Infection, n (%) | 23 (30.3%) | 221 (29.8%) | 0.892 | 19 (32.2%) | 18 (30.5) | 0.843 |
 Peripancreatic necrosis infection, n (%) | 11 (14.5%) | 75 (10.1%) | 0.324 | 9 (15.3%) | 15 (25.4%) | 0.170 |
 Gastrointestinal bleeding, n (%) | 1 (1.3%) | 3 (0.4%) | 0.323 | 1 (1.7%) | 1 (1.7%) | 1.000 |
Pain duration,d | 2.5 ± 1.1 | 1.8 ± 1.2 | 0.117 | 2.5 ± 1.1 | 2.9 ± 1.3 | 0.247 |
NOP duration, d | 2.9 ± 1.0 | 2.1 ± 0.9 | 0.122 | 2.9 ± 1.1 | 3.3 ± 2.1 | 0.142 |
ICU LOS, d | 3.0 ± 1.9 | 1.2 ± 0.7 |  < 0.001* | 3.0 ± 1.8 | 3.4 ± 2.2 | 0.067 |
Hospital LOS, d | 12.7 ± 5.4 | 10.3 ± 5.1 | 0.141 | 12.9 ± 5.5 | 16.3 ± 7.7 | 0.047* |
Hospital costs, CNY | 26,517.2 ± 2832.6 | 18,246.2 ± 5146.5 |  < 0.001* | 25,348.4 ± 2512.6 | 32,421.7 ± 2813.3 | 0.002* |