Table 4 Univariate analysis for severe intraoperative bleeding (EBL ≥ 492 mL) and postoperative bleeding complication
|  |  | Severe intraoperative bleeding (EBL ≥ 492 mL) | Postoperative bleeding complication | ||
|---|---|---|---|---|---|
Variables | n = 732 | Present | p value | Present | p value |
Age (years) | |||||
 < 65 | 475 | 9 (1.9%) |  < 0.001 | 1 (0.2%) | 0.002 |
 ≥ 65 | 257 | 35 (13.6%) |  | 7 (2.7%) |  |
Sex | |||||
Female | 332 | 12 (3.6%) | 0.001 | 5 (1.5%) | 0.327 |
Male | 400 | 32 (8.0%) | Â | 3 (0.8%) | Â |
BMI (kg/m2) | |||||
 < 22 | 333 | 18 (5.1%) | 0.437 | 4 (1.2%) | 0.282 |
 ≥ 22 | 259 | 18 (7.0%) |  | 1 (0.4%) |  |
Charlson comorbidity index | |||||
1–2 | 708 | 40 (5.7%) | 0.061 | 6 (0.9%) | 0.001 |
3–6 | 24 | 4 (16.7%) |  | 2 (8.3%) |  |
ASA・PS | |||||
1–2 | 663 | 26 (3.9%) |  < 0.001 | 4 (0.6%) |  < 0.001 |
3–5 | 69 | 18 (26.1%) |  | 4 (5.8%) |  |
Antithrombotic drugs | |||||
Absent | 668 | 37 (5.5%) | 0.113 | 5 (0.8%) | 0.004 |
Present | 64 | 7 (10.9%) | Â | 3 (4.7%) | Â |
Antiplatelet drugs | |||||
Absent | 682 | 42 (5.8%) | 0.291 | 6 (0.9%) | 0.113 |
Present | 50 | 2 (15.4%) | Â | 2 (3.9%) | Â |
Anticoagulant drugs | |||||
Absent | 722 | 42 (5.8%) | 0.223 | 6 (0.8%) |  < 0.001 |
Present | 12 | 2 (15.4%) | Â | 2 (15.4%) | Â |
Dual antithrombotic drugs | |||||
Absent | 730 | 44(6.0%) | 0.618 | 7 (1.0%) |  < 0.001 |
Present | 2 | 0 | Â | 1 (50.0%) | Â |
Malignancy | |||||
Absent | 700 | 38 (5.4%) | 0.011 | 7 (1.0%) | 0.258 |
Present | 32 | 6 (18.8%) | Â | 1 (3.1%) | Â |
Appendectomy | |||||
Absent | 297 | 41 (13.8%) |  < 0.001 | 8 (2.7%) | 0.001 |
Present | 435 | 3 (0.69%) | Â | 0 | Â |
Gastrectomy | |||||
Absent | 728 | 42 (5.8% | 0.014 | 8 (1.1%) | 0.833 |
Present | 4 | 2 (50%) | Â | 0 | Â |
Patch repair | |||||
Absent | 698 | 42 (6.0%) | 0.974 | 7 (1%) | 0.288 |
Present | 34 | 2 (5.9%) | Â | 1 (2.9%) | Â |
Colectomy | |||||
Absent | 669 | 25 (3.7%) |  < 0.001 | 6 (0.9%) | 0.096 |
Present | 63 | 19 (30.2%) | Â | 2 (3.2%) | Â |
Intestinal surgery | |||||
Absent | 584 | 30 (5.1%) | 0.061 | 5 (0.9%) | 0.221 |
Present | 148 | 14 (9.5%) | Â | 3 (2.0%) | Â |
Cholecystectomy | |||||
Absent | 697 | 41 (5.9%) | 0.537 | 7 (1%) | 0.304 |
Present | 35 | 3 (8.6%) | Â | 1 (2.9%) | Â |
Drainage operation | |||||
Absent | 7719 | 42 (5.8%) | 0.223 | 7 (1.0%) | 0.021 |
Present | 13 | 2 (15.4%) | Â | 1 (7.7%) | Â |
Surgical approach | |||||
Laparoscopic surgery | 404 | 6 (1.5%) |  < 0.001 | 1 (0.3%) | 0.015 |
Laparotomy | 328 | 38 (11.6%) | Â | 7 (2.1%) | Â |
Energy device | |||||
Present | 395 | 27 (6.8%) | 0.307 | 3 (0.8%) | 0.348 |
Absent | 337 | 17 (5.0%) | Â | 5 (1.5%) | Â |